For how we live.
Health news from around the world, organized by region.
A surveillance analysis of WHO data from January 2024 to February 2026 tracks the clade Ib emergency from declaration to its end, and finds reported spread continued after the emergency was formally lifted.
A modelling study of Koungou village, calibrated to daily cases by vaccination status, estimates CVD 103-HgR prevented 87% of cholera and averted hundreds of cases — a first real-world test of a challenge-trial vaccine.
In 544 pregnant women followed across Rio de Janeiro state, adverse maternal outcomes hit 18% of confirmed Oropouche infections versus 7% without, with fetal loss and haemorrhage risks roughly tripled.
The infections, detected across six regions between January and early October, had no links to one another. Globally MERS-CoV has caused 2,643 cases and 965 deaths since 2012.
A Quezon City hospital reviewed 20 children admitted with subacute sclerosing panencephalitis over 16 years. A quarter arrived in 2022, and the timing points back to the 2018–2019 measles outbreak.
A four-branch surveillance study in children found 2024 Mycoplasma pneumoniae incidence of 546 per 100,000, and genome sequencing showed four new subclades had replaced older lineages by mid-2024.
A Valencia hospital reviewed 108 patients with Candidozyma auris candidemia over eight years. Metastatic infection occurred in 22 percent and roughly doubled the risk of death at 60 and 90 days.
Among 93,406 children in Japan's national birth cohort, preterm birth was linked to higher odds of thinness at ages 4 to 6 and persistently lower BMI from 3 to 6, with no sign of catch-up.
A prospective UK surveillance study followed 210 pregnancies in 209 women with a pre-pregnancy cardiomyopathy diagnosis over three years. There were no maternal deaths; 10% had heart failure and 8% an arrhythmia.
In 221 male childhood-cancer survivors, FSH levels during puberty tracked adult testicular function. Radiotherapy damage persisted into adulthood, while alkylating-chemotherapy effects often recovered.
A national surveillance study found 415 children under 15 among Sierra Leone's 2024–2025 clade IIb mpox cases — three died, three-quarters needed hospital care, and household contact was the top documented exposure.
A Global Burden of Disease analysis found early-neonatal mortality in Kazakhstan dropped about 33% from 2010 to 2023 — yet boys kept dying at higher rates than girls, a gap that only recently began to close.
A Global Burden of Disease analysis puts substance use disorder prevalence at 0.78% across the Arab League in 2023, about 63% below the global figure — yet women's opioid prevalence topped men's in 19 of 22 countries.
A Global Burden of Disease analysis of Kenya's 47 counties found ischaemic stroke killed 11,328 people in 2023 — death rates are falling even as new cases rise, with raised blood pressure behind 35% of the burden.
A nationwide Brazilian cohort of 4.1 million children found that babies exposed to Zika in the womb but without congenital Zika syndrome had the same pneumonia-hospitalisation risk as unexposed children.
A first-of-its-kind report from Uzbekistan puts the case-fatality rate at 8.3%. The one sign that predicted death was present in just 3.1% of patients — a warning against waiting for it.
Genomic sequencing identified Haemophilus ducreyi — a bacterium known for a sexually transmitted infection — behind roughly 403 cases in children. Of 156 swabs tested, 61.5% were positive; no yaws was found.
Nearly a third of 68 sampled cases carried the mutation that blocks first-line antibiotics — and the resistant strain hit infants under six months hardest, during an outbreak that reached 4,976 cases and 76 deaths.
A new history of Norway's 1975 ban — one of the WHO's three 'best buys' against alcohol harm — traces how it survived courts, alcohol-free beer and social media, and why pressure to modernise it worries defenders.
A new MMWR comparison of five Ebola outbreaks since 2007 shows the Bundibugyo epidemic in Congo outran West Africa and the 2018 DRC outbreak at the same point, with 2,606 deaths by day 100.
A peer-reviewed national analysis puts a figure on this spring's resurgence: 8,834 laboratory-confirmed cases, more than 70% of patients hospitalised, and incidence highest in Dhaka division.
A phase 2b trial in 4936 Gambian children missed its primary endpoint, but ETVAX cut moderate-to-severe ETEC diarrhoea by 80.6% once parasite co-infections were excluded.
In the pragmatic BEAT Tuberculosis trial, an all-oral six-month regimen cured 86.1% of patients with rifampicin-resistant TB — statistically non-inferior to the nine-month standard, with similar safety.
A national cohort of 3,584,203 people found that 96.4% of those re-tested still had a viral load below 1000 copies per mL a year later — the threshold at which HIV is not transmitted sexually.
In 643 Indian infants, an adjuvanted dose-sparing IPV with about a quarter of the antigen was non-inferior to standard IPV across all three poliovirus types — a possible answer to supply strain.
A Manaus trial found chloroquine alone let 27% of Plasmodium vivax patients relapse by day 42; dihydroartemisinin-piperaquine cut that to 2.4%. Paired with primaquine, both drugs did well.
WHO's 25 September update logs 1,133 more confirmed cases and 532 more deaths since 11 September, and two new health zones — one bordering South Sudan — widen the outbreak's reach.
A national survey of more than 120,000 children put combined prevalence at 5.4% and heavy-intensity infection below WHO's 1% elimination threshold, after ten years of preventive chemotherapy.
A regional Global Burden of Disease analysis attributes 15.8 million healthy life-years lost in 2023 to high body-mass index, and warns of a 346.3% rise in obesity among the young.
A trial across 24 Zambian clinics found a person-centred care package lifted the share of patients in care a year after a treatment gap from 51.5% to 60.1%, and halved repeat interruptions.
A mixed-methods survey of urban households challenges the assumption that city children are the reached ones, and points to antenatal care and a mother's autonomy as the levers that decide.
Varespladib, given on top of antivenom in a randomised trial in India and the USA, did not beat placebo. But it reached patients seven hours after the bite, and the authors say that timing may be the story.
In the RESPOND randomised trial, guided self-help and remote problem-solving delivered by non-professionals cut anxiety and depression scores well below usual care at follow-up.
Drawing on households across every province and region, researchers estimate a stillbirth rate of 30.5 per 1,000 births and a maternal mortality ratio of 176 per 100,000 — both above national and 2030 targets.
A review of the Africa CDC and WHO response reports 49,803 confirmed cases and 240 deaths across 28 countries, US$977 million mobilised, and just 32% of 3.1 million delivered vaccine doses administered.
Two WHO-endorsed shots are now available, but a new analysis argues the harder problem is financing them in the lowest-income, highest-burden countries. Nigerian rollout data shows demand outpacing readiness.
Measles incidence edged up and rubella more than doubled across 22 countries in 2023–2024, with outbreaks in Yemen, Iraq and Afghanistan driving the trend as second-dose coverage stalled.
The Global Burden of Disease 2023 study estimates 2.33 billion NCD incident cases and 263 million DALYs across Africa, with high blood pressure the single largest driver of the continent's NCD deaths.
A Lancet Global Health model projects that barring women from nursing and midwifery training could cut maternal care-seeking to a third of current levels and raise the maternal mortality ratio 29% to 41% by 2035.
Across 41 hospitals in 19 Asian countries, ACORN-HAI found 73.7% of severe bloodstream and ventilator infections were drug-resistant, and 37.7% of those patients died within 28 days.
In the TESEO trial, benznidazole for 30 days matched the 60-day standard for clearing the parasite and caused fewer side effects, pointing to a gentler regimen for a neglected disease.
Analysing 32,294 viral sequences from 16,428 people, Swiss researchers found 23 fast-growing clusters drove a third of recent transmission growth — evidence molecular surveillance could target the remaining chains.
An observational study across four DR Congo outbreak sites estimates that a third of positive mpox PCR results reflect environmental viral DNA, not infection — and that a stricter cutoff fixes most of it.
As RTS,S reached more than 2 million children in Ghana, Kenya and Malawi, a WHO-coordinated pilot trained about 6,000 health workers to detect and report side-effects that most rollouts assume can already be caught.
In the LATA trial across four countries, 0.9% of teens on long-acting cabotegravir–rilpivirine lost viral suppression by 96 weeks, versus 6.4% on daily tablets — a superiority result.
A modelling study finds South Africa's selective birth-dose policy is efficient per infection averted, but giving every newborn a dose would prevent the most disease and be the most cost-effective overall.
By 2023, 22% of children in Mali and 16% in Chad had received no routine vaccine at all, an analysis of WHO figures found, with measles coverage stuck below 90% across most of the belt.
A national analysis of 2020–2025 surveillance found a case fatality rate of 15.5% that never improved, a season tied to heat and rainfall, and a falling share of suspected cases ever confirmed.
In one civilian-hospital series, 84.6% of wound isolates were multidrug-resistant; in a military cohort, 60% of Pseudomonas isolates were extensively drug-resistant. The war is also a resistance event.
A 2026 review reports more than 70 health facilities destroyed in North Kivu, 7.3 million people displaced and over 2 million children acutely malnourished, as conflict compounds overlapping outbreaks.
Bangladesh was validated in 2023 as the first country to eliminate visceral leishmaniasis as a public health problem; India is nearing the same threshold, even as post-kala-azar skin cases climb.
External validation of the PAANTHER decision algorithm in 277 children across four African countries recorded 93.3% negative predictive value and 97.4% sensitivity against a composite reference standard.
Fighting after the 2021 coup concentrated where hospital access was already worst. The population living with both poor access and intense conflict rose from 0.4 to 3.1 million in three years.
A Global Burden of Disease 2023 study counts 1,102,794 incident tracheal, bronchus and lung cancers in Asians aged 60 and over in 2023, with ageing populations set to sustain the burden even as rates fall.
A controlled study tied Scotland's minimum unit price to a 13.4% fall in deaths wholly caused by alcohol, largest in the most deprived areas. The effect on hospital admissions was smaller and not significant.
A survey of 1,042 people in the Syrian city found high prices the leading barrier, and more than half said they knew of deaths they attributed to medication shortages.
A meta-analysis of 56 trials and 134,424 children finds RTS,S and R21 cut clinical malaria by about a third overall, with efficacy strongest alongside seasonal chemoprevention and waning after 36 months.
A cohort at Kilifi County Hospital found RSV pneumonia killed 2.4% of admitted infants across 25 seasons, with no decline; severe undernutrition and congenital heart disease marked the highest risk.
A 1,784-child randomised trial in Uganda found one-fifth and one-half doses of the 17DD vaccine matched the full dose for initial immunity — evidence for dose-sparing in young children when supplies run short.
A descriptive study using WHO modelled estimates for 2022 put current cigarette use between 1.7% in Ghana and 18.2% in Seychelles, with the male-female gap reaching 36.4 points in Lesotho.
The vaccines and antibody drugs that cut Ebola's death rate work against the Zaire species. None is approved for the Bundibugyo virus now driving the largest Ebola outbreak in Congo's history.
In UK Biobank participants tracked with wrist light sensors, high nighttime light exposure was tied to thickened, weaker heart muscle and 24–33% higher risks of heart attack, stroke and heart failure.
The E-MOTIVE trial, across 80 hospitals and 210,132 births in four African countries, paired objective blood measurement with a first-response bundle — and severe outcomes fell sharply.
A Danish study of 71,000 cases found the risk factors tied to a diagnosis weakened over a decade, pointing to changing diagnostic practice rather than falling thresholds of impairment.
WHO's 10 September update records 963 more confirmed cases and 481 more deaths in the DRC since late August, with the case fatality ratio holding near 48%.
In half a million Chinese adults, higher exhaled carbon monoxide tracked with lower Parkinson's risk even among people who never smoked. It is an association, not a therapy.
A Global Burden of Disease 2021 analysis of 5-to-9-year-olds finds falling disability rates worldwide, yet projects that South and Southeast Asia and sub-Saharan Africa will still carry the heaviest load.
A five-year panel study found sales of mental-disorder medicines rose 144% in a cyclone's landfall year and 173% the next in coastal districts, with no measurable effect further inland.
Spain's PREDIMED trial is the strongest randomised evidence that a dietary pattern lowers cardiovascular events. In 2018 its authors withdrew it over flawed randomisation and reissued corrected results.
Human cases are a rounding error against the 3.5 million of the 1980s. But 684 animal infections, most of them dogs in Chad, now stand between the programme and eradication.
A WHO data-set analysis shows how mobile and hospital teams split the load of hypertension, diabetes and epilepsy care during the war, while a separate study tracked dialysis capacity falling.
Among 383 dialysis patients, 83.6% screened for moderate-to-extreme anxiety and 58% for PTSD; a separate study of 250 displaced adolescents found trauma exposure tracking closely with post-traumatic symptoms.
A single infusion of a pan-serotype monoclonal antibody cut viraemia and shortened fever in a 250-patient phase 2 trial in India — the first therapy to show preliminary efficacy against wild-type dengue in people.
Linking exome data to electronic medical records solved 15% of unexplained hearing-loss cases and flagged new candidate genes — while showing what the records could not supply.
WHO validated Bhutan's elimination of dog-transmitted human rabies, a disease almost always fatal once symptoms appear. The country has recorded zero such deaths since June 2023.
WHO validated Timor-Leste's elimination of trachoma, the last suspected focus in its South-East Asia Region. A 2025 survey of 4,949 young children found no transmission requiring intervention.
Severe dehydration from diarrhoeal disease and sepsis can shut down the kidneys. In a health system with little dialysis, a review argues this is a preventable driver of death that surveillance is missing.
WHO recorded serogroup W135 disease in pilgrims returning from Saudi Arabia in early 2025. A modelling study estimates high vaccination coverage would cut expected cases by more than 80%.
Across 166,390 tests during Brazil's outbreak, two TAK-003 doses were 73% effective against symptomatic dengue and 88% against hospitalisation, with no sign of waning.
Among 3,032 couples sampled before conception, higher maternal and paternal vitamin B12 both tracked with lower predicted birth-defect prevalence. The paternal pattern was weaker, and this is observational.
Ervebo was licensed against Zaire ebolavirus. WHO says it is not known whether it protects against Bundibugyo virus in humans — which is why a trial is running alongside the wider rollout.
The 2012 safe harbour for 3Rs data was barely used. The replacement is a voluntary pilot that takes submissions independently of a marketing application, running until the third quarter of 2027.
A Shanghai study of 3,032 couples measured nutrients before conception. Predicted birth-defect prevalence fell across maternal B12 levels — and, more weakly, across paternal ones.
One study maps the five barriers that delayed life-saving crush-syndrome care; another finds the long-term health burden of the disaster fell hardest on young women.
Most people who presented did not have diagnosed asthma. The investigation into the 2016 epidemic thunderstorm asthma event identified who was at risk, and it was not who health services expected.
A self-reported cross-sectional study of 599 residents found sharp deterioration across every measured dimension of oral health during the war — a neglected corner of the humanitarian-health picture.
Across 24 official German licensing exams, the best model answered 99.31% of first-exam items correctly. On items containing an image, the error rate rose several-fold, against 1.24x for students.
Thirty-two interviews across Uruguay, Argentina, Chile and Mexico find implementation turned on governance, not software. A separate patent analysis shows where digital therapeutics are not being built.
A review by the country's Public Health Authority credits enforcement and awareness campaigns for falls in crashes, deaths and injuries from 2013 to 2023 — while naming what still holds the Vision 2030 target back.
The association was strongest where the air was worst — which is the tell. A parallel US survey finds the indoor facilities are the ones vanishing from low-income neighbourhoods.
STAREE randomised 9,971 Australians aged 70 and over to atorvastatin or placebo. Cardiovascular events fell by 30%. Death, dementia and persistent disability, taken together, did not move.
THESUS-HF II enrolled 1,578 patients across 50 hospitals in 17 countries. Guideline drugs were prescribed at discharge in most patients, and target doses were reached in fewer than half.
Dust sampled inside 38 schools in Calama carried copper, arsenic, lead and molybdenum at levels that tracked the outdoor air — with almost no attenuation for arsenic and lead.
In 4,868 clozapine users followed to 2023, excess neutropenia risk concentrated in the first 18 weeks and converged with other antipsychotics by around two years.
In 2,292 hip fractures across six cities in Nagano, snowfall raised the odds of admission — until the models adjusted for how cold it was, at which point the association disappeared.
A facility-based study of 5,053 infants finds undernutrition begins earlier than the age group nutrition programmes usually screen — and that weight-for-age caught far more of it than arm-circumference tape.
National surveys show risk behaviours climbing among adults with diabetes since 2007, while a separate study finds noncommunicable-disease mortality nearly twice as high in the worst-affected province as in the best.
WHO's latest update records 1,129 more confirmed cases in twelve days and a case fatality ratio of 48.1%. Transmission is now confined to Congo, across 60 health zones in six provinces.
A 14-year hourly analysis of the heat index finds a rising trend and a 2025 that set records, with a 'feels-like' temperature reaching 52C as early as 7am on some days.
A 740,744-child natural experiment tested a decade-old hypothesis that rotavirus vaccine might prevent type 1 diabetes. It found no protective effect — and no evidence of harm either.
A 293-woman Dutch trial found more women reported improvement at 12 months with perioperative oestriol cream than placebo. Anatomical success, surgical success and reintervention were unchanged.
National surveillance shows no decline from 2020 to 2024, with one in five patients already disabled at diagnosis — a marker of late detection even as the global burden falls.
Papers in WHO EMRO's journal document multidrug-resistant hospital infections in Saudi Arabia, unaffordable injectable antibiotics in Iran, and antibiotic use without prescription in displaced Syrians.
A frontier analysis of two decades attributes 97.6% of nutritional disparities between countries to inefficiency rather than to resources. The policy reading is contestable; the decoupling is not.
SleepCARE randomised 219 Australian women receiving chemotherapy for breast cancer to CBT-I, bright light therapy, both, or sleep hygiene. Only CBT-I moved insomnia — and nothing moved fatigue.
A UK survey of 26,322 urban adults finds a small but consistent life-satisfaction gain from neighbourhood greenery. A Stockholm study of 46,282 shows who ends up living without it.
The country's blood-spot programme has run since 2003 and reaches nearly every baby. A pilot adds genomic sequencing — where a study of Qatari genomes suggests the biggest gains lie.
In South Kivu, ophthalmologists examined 310 patients with confirmed clade Ib mpox at four time points. Periorbital lesions and severe acute malnutrition tripled the risk of ocular involvement.
A study of 806 suspected cases found nearly a quarter were confirmed Crimean-Congo haemorrhagic fever, all the main risk factors tied to livestock handling — as warming expands the range of the ticks that carry it.
A regional review finds heat-protection for outdoor workers still leans on limiting work hours, while separate papers link chronic heat exposure among Gulf migrant labourers to a non-traditional form of kidney disease.
Italy logged 296 locally acquired cases in 2024, a European record. Transmission rose 19.8% per 1°C of warming, and modelling puts most of France in range for the mosquito that carries it this century.
The ODDESSI trial ran in 30 clusters across five NHS trusts in England. Time to relapse was unchanged; inpatient admission, re-referral and service-user ratings all moved in Open Dialogue's favour.
A national survey finds treatment volumes above 2021 levels and linear accelerators replacing cobalt-60 units. Nearly every department still using cobalt says replacing the source is now unfeasible.
Peer-reviewed work in 2026 argues the effects reach past medicine shortages into financing, procurement, workforce and continuity of care — and frames the finding as association, not proof of cause.
Before October 2023, Palestinian health authorities had documented 50 people living with HIV in Gaza. A viewpoint argues the collapse of testing and treatment has since erased that count entirely.
A 4,066-person survey series across Funafuti and the outer islands links second-hand smoke exposure — reported by 61% of participants — to obesity and elevated STOP-Bang scores.
A mandatory citywide programme sequenced 782 genes in 1,000 prospective couples. The at-risk rate was double that of a comparable Australian study, and most flagged couples still chose to marry.
A prospective study of 660 Syrian refugees living with noncommunicable diseases found symptom burden peaked in the hottest, dustiest period — with asthma and hypertension carrying the highest risk.
A registry analysis of Abyan Governorate from 2020 to 2024 puts numbers on a vaccine-preventable disease that returned as immunisation coverage fell — with the heaviest toll among children aged 5 to 9.
Adult TB incidence and mortality are projected to fall 46% and 54% by 2030, short of the 80% and 90% goals. Wider symptom-driven testing matters most to closing the gap, the analysis suggests.
A geostatistical re-estimate puts the global toll at 2.1 million envenomings and 274,000 deaths a year at minimum, with African incidence nearly three times South Asia's — against a short antivenom supply.
Each 1 degree C rise in average maximum wet bulb globe temperature across pregnancy was associated with 64% higher odds of a higher stress category — an association, in one cohort, with no mechanism established.
Among 17,508 notified cases from 2007 to 2021, 1.49% died of Chagas and 5.83% of other causes — with digestive complications, not cardiac ones, carrying the highest cumulative risk.
The tool reads vital signs, lab results, and history the way clinicians already do — just faster and continuously. Its accuracy tops out around 90%, which means it's also still wrong a meaningful share of the time.
The emergency funding is meant to keep trauma care, disease surveillance and maternal care running in Lebanon, Iran, Iraq, Syria and Jordan, atop a regional appeal only 37% funded.
Twenty hospital and health-facility projects, worth $462 million, are meant to reduce how often Kuwaitis have to travel overseas for specialized care. Thirteen are already under construction.
The country became the first in its region to receive shipments through a WHO-backed platform supplying 46 essential cancer drugs — refugees included, at no cost.
The reform followed an investigation into training quality at some foreign schools. It is also projected to disproportionately affect Arab professionals, a large share of those graduates.
The committee that decides what Israel's national insurance covers added new cancer and depression drugs to the 2026 list — and turned down an early Alzheimer's treatment because of what it would have cost.
Under-25s lost about 5 points on a 100-point wellbeing scale between 2019 and 2021. Adults 19 to 24 have clawed back two-thirds of that loss. Teenagers 15 to 18 have recovered barely a third.
PBAC recommended subsidized listing in November 2025 for adults with obesity and a history of heart attack or stroke. Price negotiations with Novo Nordisk had not concluded.
Vaping among 18-to-35-year-olds fell from 17.3% to 14.2% in a year, a real decline but a small one against how much vaping had grown before the crackdown.
The national framework tracking First Nations health finds real progress on smoking, education and specific diseases, alongside no movement on infant mortality and worsening suicide.
A $7.9 billion program now pays practices an additional 12.5% on top of the standard Medicare rebate for every bulk-billed visit — split evenly between the clinic and the doctor who sees the patient.
The new Aged Care Act mandates 215 minutes of direct care per resident per day. Since April, providers who don't actually deliver those minutes lose funding over it — not just a warning.
A surveillance analysis of Sistan and Baluchestan finds confirmed and probable cases falling from a 2019 peak, with an 11% fatality rate and a clear winter clustering.
Nigerian adults scored well below US and Norwegian comparison samples on a six-dimension sleep health measure. In South Africa, students with backup power were far less likely to report worse sleep during outages.
Only three of the 15 studies pooled in a Chilean meta-analysis used sleep testing at all. A Lima clinic analysis shows why that shortcut matters.
A 100-child randomized trial in Uganda found a cheap supplement lowered infection rates on top of standard hydroxyurea therapy — though the authors say it needs a bigger trial before it changes practice.
Seventy-seven thousand fewer children got PEPFAR-supported HIV treatment in 2025 than the year before. UNAIDS warns permanent cuts could mean millions of additional infections and deaths by 2029.
England's A&E departments handled 2.5 million attendances in July alone. Nursing staff say wards without air conditioning are becoming an occupational-safety problem, not just a patient-comfort one.
429 cases across nine countries, and a mosquito species that transmits two other viruses now established in 16 European countries — double the number from twelve years ago.
Coverage access rose from 86% to 96.4% of the population in four years. The government's own target — 80 years by 2030 — is now less than a year of progress away.
An analysis of a decade of surveillance data shows the system leans heavily on hospitals and misses cases in the community — the weakness that lets measles circulate undetected between outbreaks.
The Dubai Longevity Authority will oversee everything from lab research to the clinics selling anti-aging treatments — a regulatory structure that doesn't really exist yet anywhere else.
The Bundibugyo virus epidemic is now the largest Ebola outbreak in Congo's history. WHO's emergency committee met again this week; MSF says the response still isn't reaching people fast enough.
More than 410,000 probable cases so far in 2026, against 1.45 million for all of 2025. One state, Minas Gerais, accounts for roughly a sixth of the national case total on its own.
Fatal disease burden fell 10% in two decades. Non-fatal burden — the toll of living with illness rather than dying from it — rose 7% over the same period. Mental health diagnoses in young adults nearly doubled.
Cross-sectional studies from the country's south and east report about a third of respondents vaping, with attitudes — not knowledge — the factor most strongly linked to use.
A 422-family cohort with a pre-ban baseline is the closest thing to a controlled test the world has. Researchers are also warning the law will make studying adolescents harder — including studying this.
A review pooling prevalence across the region ties the projection to modifiable risks that are unusually common there — smoking, inactivity, diabetes — layered on rapid ageing.
A systematic review of the Syrian crisis and infectious disease in Lebanon names overcrowding, poor sanitation and blocked healthcare access — not the presence of refugees themselves — as the reported drivers.
ACT-South Asia randomised 1,847 patients in Nepal, Bangladesh and Pakistan. Treatment failed in 5.1% of each group — no benefit from the second antibiotic, and a point in favour of stewardship.
Chronic granulomatous disease is usually X-linked in Western cohorts. A multicentre Middle East and North Africa registry found the opposite pattern, alongside late diagnosis and a median survival of 8.5 years.
A narrative review synthesising WHO, UNRWA and Gaza health-ministry field data reports the re-emergence of hepatitis A and poliovirus, over 200,000 diarrhoeal cases, and drug-resistant hospital pathogens.
A cluster-randomised trial in Cúcuta coated water containers in 13,803 homes. Dengue incidence fell to 337 per 100,000 versus 528 in control clusters, at about US$2 per household a year.
A national analysis of 2,985 haemorrhage deaths from 2015 to 2024 found no significant change over time — and Indigenous women dying at 2.87 times the rate of White women.
VPM1002 did not show non-inferiority to BCG for preventing tuberculosis infection in a phase 3 trial across sub-Saharan Africa. Far fewer infections occurred than planned, leaving the comparison unresolved.
A decade of eardrum repair delivered on Country across nine Queensland communities produced closure rates below metropolitan benchmarks — and a follow-up rate most urban surgical services do not achieve.
New GBD analysis across 21 countries finds one group whose burden fell — children — while incidence rose 92% overall and the sex pattern inverted.
Researchers modelled 854 European cities under the climate that exists and the one that would have existed without human warming. The attributable share rose from 45% to 64%.
A national study built for Australia's first Climate Risk Assessment separates the two exposures across ED, inpatient, GP and prescription data. They do not act on the health system the same way.
A rescreen of 1,000 acute febrile illness samples from Loreto found the virus circulating endemically rather than in a single outbreak, including in a remote riverine community.
Surveillance data show reported measles cases from Tigray collapsed during the 2020–2022 war; afterward the median age of infection fell to five years and the odds a case was unvaccinated stayed sharply raised.
A case-control study by MSF's Epicentre and WHO put NmCV-5's adjusted effectiveness at 92% against meningococcal meningitis after 2024 campaigns in Niger — on a small sample of 17 confirmed cases.
A case-crossover study of 29,604 arrests over a decade found risk lowest around the 86th temperature percentile and higher at both local extremes, with the cold tail slightly larger.
The Pittsburgh Sleep Quality Index global score is the field's default outcome. Tested in a large South African cohort, its single-factor structure fit poorly and internal consistency was modest.
A rare multicentre record from three Sudanese trauma centres finds penetrating injury in more than nine of ten patients, and civilians in the great majority.
In 2,414 children, the MODAM-MAM trial found one daily sachet of therapeutic food non-inferior to standard supplementary food; two sachets did marginally better but used far more product.
A Brazilian laboratory study found both a prototype strain and an emergent reassortant killed neural progenitors and collapsed cortical structure. This is a dish, not a pregnancy.
Children in low-vegetation districts exposed to heat stress had sharply higher odds of severe wasting and underweight; in greener areas the link vanished. The pathway runs through food systems, not heat alone.
START-AI reads triage comments, case notes and whether anyone ordered a blood test. Adding heart rate and blood pressure to the model produced no measurable improvement — a result the team published rather than buried.
In 555,904 matched adults, screening endoscopy cut gastric cancer mortality in the 50s and 60s. Past 80, or with heavy comorbidity, the association reversed.
ECDC data show near-zero hepatitis B in under-fives and vertical transmission below 2%, alongside five million chronic infections and only seven countries meeting the harm-reduction benchmark.
Two national survey analyses find schedule unpredictability — not shift work itself — associated with insomnia symptoms, with a dose-response by how much advance notice a worker gets.
A study of 1,331 physicians put violence ahead of pay. Of 32 doctors who had already emigrated, two were considering coming back — and none of the women were.
A community study of 2,340 residents, run after the conflict that wrecked the region's health system, found presumptive tuberculosis above 10% in both town and countryside.
A cross-sectional study of 96 war amputees, 53 caregivers and 95 community controls found sharply elevated disability and psychiatric symptoms, and argued for combined physical and mental-health rehabilitation.
A comparative survey finds four European countries still rely on opportunistic screening, and that where family doctors are most involved, participation tends to be lower — not higher.
A blinded comparison of 180 responses from a university telehealth centre in Minas Gerais found AI matched human specialists on medical adequacy and risk, and beat them on comprehensibility.
A cluster-randomised trial in Saponé found seasonal chemoprevention given to children up to age 10 nearly halved parasite carriage in 5-to-9-year-olds, though supervised delivery brought no clear gain under age five.
Nine countries have launched lenacapavir for HIV prevention, with roughly 66,000 people newly started on it. In at least two countries, demand has already outrun the available doses.
Sixteen years of PCR-confirmed data show Buruli ulcer incidence down nearly 80%. Over the same period open water surfaces shrank 25–30% and mean air temperature rose by more than 1°C.
A comparison of 2020–2025 approvals finds 94 novel oncology drugs from the NMPA against 87 from the FDA, with China's volume overtaking from 2023. The speed and first-in-class figures run the other way.
A registry study spanning 4.9 million people separates where the most deaths occur from where the inequality is largest. Heart disease and lung disease give different answers.
In the first humanitarian trial of its kind, 400 refugees and hosts were randomised. AUDIT scores fell 4.6 points more with screening and brief intervention than with usual care at six months.
Blood samples from a West African vaccine trial show both licensed Ebola vaccines generate antibodies that bind Bundibugyo virus — the species with no vaccine of its own, now causing DRC's largest outbreak on record.
Peruvian Andeans are famous for high haemoglobin at altitude. A genome-wide scan finds the alleles under recent positive selection are the ones that lower it — a pattern closer to Tibetans than expected.
A first consolidated audit of PBS and PHARMAC cardiovascular listings from 2023 to 2025 finds a widening access gap between two neighbouring countries with similar disease burdens.
An analysis of 15 years of case data from Altamira, in the Xingu Basin, finds forest edge and local population size — not climate — explained where transmission returned.
The CHMP's June meeting recommended pulling avacopan from the EU market on data-integrity grounds, refused three cell and biological therapies, and reversed itself on a Rett syndrome drug it had earlier rejected.
Two months after the emergency declaration, confirmed cases in DRC have passed 2,100 and spread to 46 health zones. There is still no approved vaccine or treatment — but patients are now being enrolled in one.
A twelve-athlete study tested morning, late-afternoon and late-evening sessions across the fasting month — and found the deficit was specific to time of day, not spread evenly across it.
Two 2026 papers describe the same shift: rural incidence now exceeds urban in some years, the peak has slid to October and November, and one in six hospitalised patients progressed to severe disease.
Four years after the virus was first detected in south-eastern Australia, interviews in Tamworth find eligibility for a free vaccine has not translated into uptake.
A peer-reviewed account traces the mass screening and tsetse-fly control that cut gambiense sleeping sickness below one case per 10,000 in endemic areas — the threshold WHO validated in January 2025.
Fine particulate exposure in seven Amazonian capitals was tied to about 5,472 circulatory and 2,621 respiratory deaths over six years. A separate analysis finds cardiac mortality rising with forest loss.
A registry snapshot of 13,455 adults measures how far the biologic era has moved severe asthma toward remission, and finds the inflammation these drugs target still detectable in most patients.
A 398-caregiver study across all five island groups finds the single biggest predictor of HPV vaccination was knowing the vaccine was free — after a decade of the programme running.
Stress peaked during the fasting month and fell afterwards, but depression and anxiety stayed flat. The consistent finding across every phase was that sleep quality tracked mental health.
An all-oral short regimen, its length set by chest-imaging severity, was non-inferior to 18-month treatment and caused fewer serious adverse events in a Chinese randomised trial.
Across 84,348 hospital admissions, 19.8% of children had severe anaemia; as malaria receded the burden moved to older children, and severe anaemia doubled the odds of dying.
A New England Journal of Medicine review of the ongoing outbreak lays out what is and isn't known about treating Bundibugyo virus disease — and why Ebola virus countermeasures may offer partial cover.
Maccabi Healthcare Services studied 626 of its own physicians to work out who follows algorithmic prescribing advice — and found the pattern was about practice structure, not just attitude.
A quasi-experimental analysis of 23 hospitals finds about 95 additional self-harm and suicide-related emergency visits a month after the law changed, alongside fewer psychiatric admissions.
A WHO global update logged 79 human infections in the Americas and 16 confirmed cases in Africa by late May, with the virus surfacing in areas long considered free of it.
A burden-of-disease calculation built on EU noise-mapping data puts numbers on two outcomes that noise research has mostly ignored. The confidence intervals are as informative as the estimates.
A single patient is on ventilatory support in Kozhikode. WHO says 104 contacts are being monitored and the source of infection has not been identified.
Five weeks into the Bundibugyo virus emergency, WHO says some new cases reflect transmission that had gone undetected for weeks — a sign the outbreak may be larger than the count shows.
A Bulletin of the WHO study recorded 168 maternal deaths between October 2023 and June 2024, alongside higher stillbirth, neonatal-death and preterm-birth rates than before the war.
Guangdong recorded 25,335 local cases in 2025 — 98% of everything China has ever reported. Genomic analysis finds every Chinese outbreak lineage matching a recent import.
A stepped-wedge trial across 165 women's and girls' Australian football teams shows how far implementation support moves uptake — and how much larger a trial would need to be to prove it prevents injuries.
Data from 20 European countries covering 2014 to 2024 tracks lung function, nutrition and infection through the arrival of triple modulator therapy — and the new complications arriving with age.
A scoping review of 171 studies found output peaked in 2019, fell during COVID, and left the genomic surveillance of a coronavirus with pandemic potential thinly covered.
Extremely dense breasts on a routine screening mammogram were linked to a 20% lower likelihood of menopause over the following years, a possible marker of reproductive aging.
Two peer-reviewed studies chart the toll: among 122 Khartoum dialysis patients followed for up to 18 months, 53% survived, and those who stayed in the capital fared worst.
Twenty-two years of national data show income-related inequities in care use narrowing, and copayment increases for higher earners not reversing that. Services carrying extra user charges are the outlier.
WHO declared a public health emergency of international concern on 17 May. By early June, confirmed cases had climbed past 500 and Africa CDC put a price tag on the continental response: $518 million.
A 23-year genetic-network analysis of 5,094 cases identified 107 molecular super-spreaders, mostly men aged 50-69, with 94.4% living within 2 km of major transport routes.
A comparison of FDA, EMA and ANVISA decisions from 2020 to 2024 finds Brazilian approvals arriving about a year later. A second study clocks the wait for public-system financing in years, not months.
A national database of ~90% of public facilities found all-cause diarrhoea incidence in under-fives dropped 50% and hospitalisations 58% after 2020, with no rise in intussusception.
After 12 months, HbA1c was 6.5% among people managed by community health workers versus 7.1% among those referred to clinics. With 103 participants analysed, the confidence interval crosses zero.
Switzerland allows limited psilocybin use for treatment-resistant depression. A review of 19 patients found meaningful improvement, but remission in barely a fifth to a quarter.
A national case-crossover study of 236,260 chronic kidney disease deaths finds women, over-65s and people in cooler regions most affected — and projects the burden nearly quadrupling by the 2090s.
A modelling analysis puts 2.75 million children under five in sub-Saharan Africa living with sickle cell disease. Seven African countries have transplant programmes; approved gene therapies cost millions.
The ESC Atlas reports 68 million disability-adjusted life years and more than three million cardiovascular deaths a year, with middle-income countries carrying roughly double the mortality of high-income ones.
A single-author analysis of Global Burden of Disease estimates finds the region's neurodevelopmental picture split in two — and argues the flat autism curve reflects diagnostic capacity, not risk.
An 8-year-old boy had brain inflammation with no respiratory symptoms. Every respiratory, blood and rectal sample tested negative; the virus was in his cerebrospinal fluid alone.
A review of 42 studies on South Africa's Comrades Marathon finds medical encounters at up to 20 per 1,000 starters — mostly dehydration and cramping, not the cardiac events that draw the most attention.
An all-oral, bedaquiline-based programme treated 277 patients through six years of conflict in eastern Congo and reached 77.6% treatment success — above WHO's 75% mark — but mortality stayed at 13.4%.
Eight confirmed cases, 246 suspected, and 80 suspected deaths in eastern DRC were enough for the Director-General to invoke his highest level of alarm — before convening the emergency committee that usually comes first.
An age-period-cohort analysis across five registries finds annual increases of 5.3% in Korea and 3.8% in Japan, against 1.6% among Japanese Americans and flat or falling rates in US White women.
A linked-registry cohort of New South Wales residents from 2001 to 2018 finds cancer risk in people with intellectual disability inverts with age — higher when young, lower after 50.
PHARMAC's October 2024 decision left one brand's sensors unfunded, forcing a device switch. A single-centre audit of 79 children found HbA1c fell slightly — and cannot say the switch caused it.
A Lancet evaluation of the RTS,S introduction in Ghana, Kenya and Malawi reports a 13% drop in mortality among vaccine-eligible children — achieved with third-dose coverage of 71% and fourth-dose uptake under 40%.
A Qatar Biobank analysis derived local cut-points and found WHO's standard numbers misclassified more than half of men and nearly half of women in the sample.
A cross-sectional analysis of NICE evaluations found 78 supporting studies behind 30 technologies — and consistent holes in comparators, cost of delivery and adverse-event reporting.
An econometric analysis of the 2019 European Health Interview Survey prices smoking-attributable inpatient and daycare hospitalisation across the EU — deliberately excluding every other kind of care.
WHO's latest mpox report shows global case counts holding steady, but flags a Sindh province cluster where nearly all deaths were in babies under six months old.
WHO's latest tally puts the 2026 year-to-date count at 58,740 cases and 732 deaths across 22 countries, down sharply from last year except in conflict-affected states.
WHO reports 19,161 suspected cases and 166 deaths in a single month, most in children under five. The country had been close to eliminating the disease.
The CHMP backed tolebrutinib for non-relapsing secondary progressive multiple sclerosis, a population with no prior disability-targeting treatment. The trial showed a 31% delay in progression.
A study across nine facilities in Makkah recorded 1,576 cases of heat exhaustion or heatstroke and a 4.9% mortality rate — in a region where heat-health research remains remarkably thin.
A Nature Communications review of the continent's biomedical data science capacity found none of 36 surveyed groups using cloud high-performance computing, and named electricity outages among the most common obstacles.
An analysis across the Premier League, La Liga, Serie A, Bundesliga and Ligue 1 found economic losses from player injuries topped 730 million euros in a season, with hamstrings hit hardest.
The LiverScreen project ran transient elastography across nine countries, then sent everyone who screened positive to a hepatologist. The gap between the two numbers is the interesting part.
Integrated risk scores combine polygenic data with conventional risk factors. A readiness review lists what would have to exist first — and separately, 36% of older Australians had no skin check at all last year.
The patient had spent months in Senegal and was found to carry the poultry-adapted virus alongside tuberculosis. WHO rates the public risk as low and traced no onward spread.
Two 2026 reviews describe the same handover: as the virus recedes, obesity-driven fatty liver disease is moving into the space it occupied — in a population where roughly 40% of screened adults met obesity criteria.
Anvisa's five new resolutions build a controlled supply chain from seed to shelf, including a regulatory sandbox for patient associations. Analysts say the framework's biggest gap is the one it did not close.
Two doses of the long-acting antibody L9LS protected under-fives in a high-transmission area, but researchers say a higher dose is likely needed for stronger cover.
Sub-Saharan Africa received $11 billion in external assistance for community health worker programmes over two decades. More than three-quarters went to single-disease work, and the annual financing gap never closed.
A six-year cohort study using Japan's long-term care records found a roughly 25% lower risk. The design cannot separate cooking from the ability to cook.
The European Medicines Agency's March meeting produced five positive opinions, three of them for orphan-designated cancer and rare-disease treatments already available in some other markets.
The barriers parents named most often were cost and the absence of any nearby service — not stigma, which the field has spent years treating as the main obstacle.
A new audit of China's regulatory record finds a market concentrated in radiology, dominated by deep learning, and clustered in four cities. It also finds the approval curve flattening.
The AVENIR trial met its resistance endpoint in the gut but not the nose: giving the antibiotic to under-fives lifted macrolide resistance 16% above placebo communities.
The estimate covers only populations in humanitarian need across Burkina Faso, Central African Republic, Chad, Mali, Niger and Nigeria — and it assumes nothing replaces the lost money.
In 30,446 Malmö residents followed for decades, each step up in soot exposure was tied to 15% higher cardiovascular mortality — a stronger, steadier signal than total fine particles or traffic gases.
The elevated risk showed up even in babies with no detectable malformation — which is not what the standard recessive-disease explanation predicts.
Fifty-five per cent of surveyed cricketers over 70 reported a basal cell carcinoma. A 29% response rate and self-reported diagnoses mean the number cannot be read as a rate — which is the finding.
The regional health agency counted 34 confirmed cases and 15 deaths in the first seven weeks of 2026, after 2025 brought the highest South American case total in over two decades.
The surveillance behind the WHO-verified milestone is now published: no infective blackflies at any monitored site, and no infection among 16,406 children tested.
A test-negative study found the TYPHIBEV conjugate vaccine 89% effective against confirmed typhoid in Nepali children over 30 months, with weaker and far less certain protection under age five.
A survey-based analysis of the European Health Interview Survey puts a price on Europe's obesity-related hospital use, and finds the strongest single association is not with obesity at all.
The first large instrumented-mouthguard dataset from elite Australian football finds women absorb greater rotational acceleration per impact, and that men's ruckmen sit in a category of their own.
PAHO counted 14,891 confirmed cases across the Americas in 2025, a 32-fold rise on 2024. Six South American countries reported cases, and only a third of the region's countries reach the coverage that stops outbreaks.
Australian teenagers harmed by the Black Summer fires showed no elevated depression, anxiety, distress, insomnia or suicidality two years later. The result runs against a systematic review published months earlier.
Sequencing 6,141 people turned high consanguinity into a research advantage: it produced natural human knockouts that population studies elsewhere almost never see.
Fourteen months after an undiagnosed febrile outbreak alarmed the world, sequencing and PCR on 108 patients found no novel pathogen — half had falciparum malaria and many had a respiratory co-infection.
The first independent population-representative mortality survey in the Gaza Strip estimates 75,200 violent deaths through early January 2025 — and finds fewer non-violent excess deaths than some models predicted.
A cluster-randomised trial across 15 population clusters found mosquito abundance collapsed in intervention areas and protective efficacy of 71–72% against symptomatic dengue.
Ten years of national anti-doping reports show NSAID declarations flat at about 45%, a significant shift away from COX-2 selective drugs, and glucocorticoids making up around 13% of all prohibited-substance findings.
A Swedish birth cohort of 2.76 million people found the cumulative male-to-female ratio for autism incidence had fallen to 1.2 by age 20 — and projects parity by 2024.
The patient drank raw date palm sap through most of January. Thirty-five contacts are under monitoring, and the six who developed symptoms have tested negative.
Seven seasons of records on 569 students found 9.0 injuries per 1,000 exposure days in the upper school. Most injuries came on gradually, and a quarter were recurrences.
A trial across five Chinese hospitals found remote robotic urological surgery non-inferior to local surgery. The sample is small, the surgeons were experts, and the network never failed.
WHO was notified on January 26 of the third Nipah outbreak recorded in West Bengal. There is no licensed vaccine or drug, and the source of exposure is still under investigation.
The PROP OA trial found a 3.39-point gain on a 100-point score at six months. The effect on pain was larger than the effect overall, and both diminished by twelve months.
A scoping review found 36 studies on heat and health, only 13 with Gauteng data. Rather than wait for more, the authors borrowed designs from Victoria, Maharashtra and Khyber Pakhtunkhwa.
In 105,260 people followed for 7.6 years, higher intakes of sorbates, sulfites, nitrates and acetates tracked with modestly higher cancer incidence. This is an observational study of self-reported diets.
The Ministry of Health declared the end on January 26, two incubation periods after the last confirmed patient was buried. No vaccine or drug for Marburg is approved anywhere.
Play was suspended on outside courts on Saturday when the tournament's five-point Heat Stress Scale maxed out. A ball kid collapsed during a match the same day. The threshold is set on physiology, not air temperature.
An 11,018-measurement study in 24 English intensive care units found false negative rates up to 35.3 percentage points higher in patients with darker skin tones. A neonatal study published two days later did not.
A January study forecasts particulate pollution across six Gulf states and reports Qatar highest at 87.90 µg/m³. The modelling is careful; the input data is annual, national and thirty-one points long.
Large taxed beverage sales fell 24 to 31 percent under the tax. In the period after repeal they remained 13 to 24 percent below pre-tax levels — and prices stayed elevated too.
Washington intends to provide up to $792 million over five years. Malawi commits the rest — and the money is meant to flow through the government rather than NGOs.
Household cure rates were 88.5 percent with permethrin against 71.8 percent with ivermectin. The trial set out to show ivermectin was non-inferior and found the opposite.
Nineteen MERS cases were reported worldwide in 2025, seventeen of them in Saudi Arabia. The two in France are the first infections detected outside the region in six years.
The first national estimate of temperature-attributable food poisoning in Australia. A companion study in Queensland tested whether heat also drives drug resistance in the same bug — and found nothing.
A year of wearable data from 76 subsistence farmers shows adaptation happening in real time. The women in the study had less room to slow down, and their strain readings show it.
Twelve years of English primary care records put a price on weather. The heat effect is loud and short; the cold effect is quiet, cumulative, and much larger.
A ten-season analysis of 3,750 matches quantifies the load argument footballers have been making. It also states plainly what it cannot show: anything about injury.
The first nationally representative analysis of the 2024 conflict in Lebanon draws on hospital and ministry records. Its most consequential number is how many of the dead arrived already dead.
Germany's DINKS trial is one of the largest randomised tests of a reimbursable digital therapeutic. The effect is big, the comparator is usual care alone, and the sponsor made the app.
Emergency restrictions came into force on 13 December when the index passed 450. The more telling number is how many days the city has now spent in a category that was meant to be exceptional.
Floods and landslides in Indonesia, Sri Lanka and Thailand have killed more people in a fortnight than most single climate events on record. The second wave — water, food, medicine — is the part that lasts.
England ran the closest thing to a national test of clinical AI anyone has published. The software sites gained more, but the comparison sites were improving on their own, and that gap is the whole result.
The Bulape outbreak in Kasai Province ended 88 days after it was declared, with a case fatality ratio above 70% and nearly 48,000 people vaccinated.
A national registry analysis found the highest burden among 20-to-29-year-olds and a notable rise among girls aged 10 to 19, with rates concentrated in the Sierra region.
A national pharmaceutical database analysis found out-of-pocket purchases accounted for 78-86% of contraceptive use, with emergency contraception priced up to 25 times higher than the insured rate.
Across 11 surveillance sites in sub-Saharan Africa, nighttime heatwave mortality risk rose between 2005-2010 and 2011-2015 — the opposite of the adaptation trend reported in wealthy countries.
Two November burden analyses put diabetes diagnosed before 40 on an upward path to 2050. In the Americas, Central Latin America carried the highest rates and men carried more of the burden than women.
WHO has graded the regional resurgence a level 2 emergency. Only 5.7% of the 20,412 suspected cases were laboratory-confirmed, and the antitoxin that prevents most deaths is in global short supply.
Nearly a million conscripts followed for three decades: obesity carried a 3.1-fold hazard for sepsis, and high cardiorespiratory fitness was associated with a 42% lower risk of dying from bacterial infection.
Shared cell time raises transmission odds sharply — six months of it doubles them. But cell-level exposure explains only part of the genomic clustering, which undercuts contact tracing as a strategy.
Six laboratory-confirmed cases and three probable ones have been reported from Jinka town. All deaths involved unsupervised burials — the step in the chain that historically turns a cluster into an outbreak.
In 59 facilities across Malawi and Uganda where 431,394 women gave birth, the APT-Sepsis programme reduced infection-related death, near-miss events and severe illness from 1.9% to 1.4%.
A Buenos Aires surveillance cohort estimates 80.8% effectiveness against RSV hospitalisation in infants under three months — close to what the licensing trial found, in a real programme.
The CHMP's November meeting produced ten positive opinions. Two of them — teplizumab and a Telethon-sponsored gene therapy — address conditions the EU has had no authorised treatment for.
Age, sex, employment and socioeconomic level together explained under 1% of variance in insomnia severity. Perceived stress and generalised anxiety explained close to a third.
A WHO and Brazil special report released on the summit's Health Day says extreme heat kills over 540,000 people a year and that health facilities face 41% higher weather-damage risk than in 1990.
WHO validated Egypt as the 27th country to eliminate trachoma as a public health problem. Its programme began in 2002; the disease still blinds or impairs about 1.9 million people elsewhere.
The 2025 Lancet Countdown Latin America report tracks 41 indicators across 17 countries. Heat-related deaths are up 103%, and fewer than half the region's governments have finished a vulnerability assessment.
WHO reports 404 confirmed human cases across the two countries in six weeks. The case fatality ratio is 30% in Mauritania and 7.8% in Senegal — a gap that says more about detection than about the virus.
A within-individual analysis of 505,474 people in Finland and Sweden found lower psychiatric hospitalisation on clozapine in every disorder studied except borderline personality disorder, with no excess mortality signal.
Among 1,000 adults in Mwanza, overnight oximetry found sleep apnea in 17% of people with HIV and 19% without. Excessive daytime sleepiness, oddly, was more common in those without HIV.
The experimental recombinant antivenom outperformed a plasma-derived product in mice and cut tissue necrosis. It has not been tested in a single human, and the paper does not address cost or manufacturing at scale.
A 43-year analysis at hourly resolution finds a 3.3% rise in average heat stress exposure duration across districts, with the change varying by time of day, season and region.
Researchers tested heat-mortality forecasts against the European summers of 2022 and 2023. The skill pattern is not the one a warning system designer would have guessed.
SURPASS-CN-INS randomised 257 adults at 26 Chinese hospitals. The 10 mg and 15 mg doses performed almost identically against placebo, and diarrhoea affected roughly a third of those on the higher doses.
The trial was designed to test non-inferiority against traditional dietary advice. It found superiority instead, with 62% versus 42% achieving a clinical response over six weeks.
Physicians editing AI drafts wrote better notes than they did unaided, and worse notes than the AI produced alone. Both directions of that result matter.
An Australian laboratory trial played 20-second noise bursts to 68 sleeping adults. Arousal probabilities were low for both, and lower for wind farm noise at 40 and 50 decibels.
A national insurance-claims analysis found long-term adherence far below what trial populations suggest, despite universal coverage and strict usage monitoring. The monitoring may be part of the problem.
Two Nature papers describe the Taiwan Precision Medicine Initiative and the risk scores built from it. The genetic effects identified explained up to 10.3% of health variation in the cohort.
Two trials showed more deaths on voxelotor than placebo. The registry data that triggered the 2024 precautionary suspension did not confirm the original signal — the trials did something worse.
A 47-prefecture analysis of a decade of heatstroke mortality finds the alert level set at 33C misses almost all of the deaths a warning could plausibly prevent. About 31C would halve them.
Brensocatib cleared CHMP on an accelerated timetable with a 19.4% cut in exacerbation rate. The same October meeting issued a negative opinion on belumosudil and kept a sickle cell drug suspended.
Age-standardised incidence was 42.3 per 100,000 in Ghana and 43.1 in US non-Hispanic Black women, against 24.0 in white women. ER-positive rates diverged sharply in the other direction.
The modelling study puts 719,384 people on PEPFAR-funded oral PrEP in 28 African countries at the end of 2024. Most projected infections fall on key populations whose coverage was already under 6%.
A UNRWA surveillance dataset of 265,974 arm-circumference measurements shows wasting rising during blockade, falling during ceasefire, then rising again — an unusually direct record of cause and effect.
A prospective cohort of 88 index cases and 432 household contacts found a secondary attack rate of 6.15%, three times higher in under-15s. The estimated R0 inside households was 0.30.
A Brazilian randomised trial found laser and radiofrequency equally effective for genitourinary syndrome of menopause. The one trial that used sham treatment found no benefit at all.
In 24,223 Swedish workers followed to 2018, insomnia and long sleep raised cardiovascular risk only when accompanied by daytime impairment — and rising sleep duration preceded disease.
Fourteen Swedish primary care patients were interviewed alongside a trial of nurse-led group sleep restriction therapy. Depression and life circumstances were what got in the way.
A high-resolution model of East Africa's most densely settled basin finds that two-thirds of the projected rise in exposure comes from temperature and population growth acting together.
BCG and oral polio vaccine given within 48 hours to 5,420 babies under 2,000 g reduced deaths from infections other than tuberculosis. The effect is off-target, and the mechanism is unresolved.
Loneliness tracked with depression, perceived stress, psychotic-like experiences and suicidal ideation. A prevalence that high raises a question about what the measure is capturing.
In a 400-pair trial in Uganda where every family already had a bed net, insecticide-treated wraps reduced clinical malaria in infants from 2.14 to 0.73 cases per 100 person-weeks.
Over 17.4 years, high ultra-processed food intake was linked to a 24% higher colorectal cancer risk overall — and a 58% higher risk for right-sided colon cancer specifically.
Across 20,121 adults and 25 years of registry data, morningness markers predicted lower educational attainment but also lower odds of the bottom income quintile. Effects were absent in women.
Twenty untrained women cycled at four fixed workloads wearing four popular low-cost bands, checked against indirect calorimetry. Every device drifted further from the truth as effort rose.
Seven of those nine were denosumab. The committee's September opinions also covered an RSV antibody for infants, a first EU treatment for IgG4-related disease, and four withdrawn applications.
A pooled analysis of 72,776 Korean adults found an 11% higher type 2 diabetes risk in the top intake quartile. An updated meta-analysis of 17 cohorts put the dose-response at 10% per 10% of intake.
Three of the four cases drank raw date palm sap in the usual December-April window. The fourth, a child who fell ill in August, did not — and the source remains under investigation.
In 99 men hospitalised for stress-related disorders, roughly four in five met probable criteria for trauma-associated sleep disorder — a condition that is not yet a recognised diagnosis.
A 50-year attribution study separates two trends that usually get modelled as one: rising temperatures and a population that has become less likely to die in them.
ALEG's position holds that testosterone in postmenopausal women should be limited to hypoactive sexual desire disorder, and that pellets and compounded formulations are not recommended.
An Australian cohort of 3,044 children found no protective factor held across all ages and outcomes. School safety mattered at age 6-7; belonging mattered at 12-13.
Across 165 clinics in four African countries, HIV testing fell by up to 35% and treatment starts by up to 32%. Most services had not returned to baseline two months after the orders were lifted.
A UK-wide survey found cognitive and psychological symptoms outranked the ones menopause care is organised around, with higher ratings among Asian and Black respondents.
In a 774-person randomised trial, community health workers delivering medication at home nearly doubled the share of patients whose blood pressure was controlled at six months.
A French prospective cohort followed adults with rare genetic obesity treated with the MC4R agonist in routine care. Weight fell about 20% in the first year and hunger scores dropped 62%.
Sequencing points to a fresh spillover from wildlife rather than a resurgence of the province's earlier outbreaks. Four of the dead are health-care workers.
An EMAS clinical guide sets out how to manage endometriosis after menopause, advising against oestrogen-only hormone therapy even in women who have had a hysterectomy.
Nine genetically linked virus isolates from seven environmental sites triggered the declaration. Sequencing traced the lineage back to a paralysis case reported in December 2024.
WHO counted 409,222 cases and 4,738 deaths across 31 countries by 17 August. The divergence between the two trends is the finding, and it points at case management, not transmission.
A Spanish trial in 4,746 adults compared an energy-reduced Mediterranean diet plus exercise against the same diet eaten freely. Over six years the absolute gap was 12.0% versus 9.5%.
A 15-city study found a pooled relative risk of exactly 1.00 for heat warnings. Adjusting for green space, population and density turned it into 0.85. Both numbers are in the same paper.
About 1,009 deaths a year were attributable to heatwaves in 2016-2019. Queensland and New South Wales carried rates more than three times Western Australia's.
Fifty-five English adults ate two eight-week diets that both followed the UK Eatwell Guide. Both produced weight loss. The minimally processed version produced about one percentage point more.
Kerala's ninth Nipah outbreak since 2018 produced four unlinked cases between April and July, suggesting separate spillovers from bats rather than a chain of human transmission.
The causes recorded do not look like a textbook heat event: nonspecific findings, nervous system disease and mental disorders led the excess, and deaths at home rose 64%.
Two BMJ reviews found high-risk usability problems in 18 of 30 tests, and use judged contrary to evidence-based guidance for 11 of the 19 conditions covered.
Singapore General Hospital randomised residents to work with and without an LLM assistant. Documentation time fell by 1.82 minutes, which was not significant. The economic model used the point estimates anyway.
In 270 patients whose voices persisted despite antipsychotics, the therapy beat matched clinical contact on hallucination severity by 2.26 points — significant, with a Cohen's d of 0.27.
WHO has logged 11 laboratory-confirmed human A(H5N1) infections in Cambodia between 1 January and 1 July, including six deaths. Every case had handled or culled sick poultry.
A study of 5,459 municipalities projects annual costs of $228-264 million by mid-century, with the largest absolute burden in the South and the fastest relative growth in the North.
In 12 clusters, 6% of girls in the intervention group experienced a maternal or perinatal death against 13% in control. The trial was a pilot, and the authors present it as such.
Deaths during combined heat and ozone days in Hong Kong, preterm births projected across Chinese cities to 2100, and a seasonal flip in Japan's ambulance demand from winter to summer.
Five cutaneous anthrax cases, one fatal, were confirmed in Mukdahan province in May 2025, all tied to the home slaughter of infected cows — a textbook zoonotic spillover.
Two healthy children in Lae tested positive for cVDPV2 genetically linked to an Indonesian outbreak, in a country where coverage for a third oral polio dose was 44% in 2024.
The final analysis of a 28,130-child trial found roughly 78% efficacy over more than four years, evidence that underpins WHO's push to roll the conjugate vaccine out in endemic countries.