Global Health

Ethiopia's first Marburg outbreak is over: 19 cases, 14 deaths, 42 days clear

The Ministry of Health declared the end on January 26, two incubation periods after the last confirmed patient was buried. No vaccine or drug for Marburg is approved anywhere.

On January 26 Ethiopia's Ministry of Health declared the end of the country's Marburg virus disease outbreak [s1]. It was the first Marburg outbreak Ethiopia has ever reported [s1].

The declaration came 42 days — two consecutive incubation periods — after the last person confirmed with Marburg died and was given a safe and dignified burial on December 14, 2025, in accordance with WHO recommendations [s1]. That interval is the standard: a filovirus outbreak is not declared over when cases stop appearing, but when twice the maximum incubation period has passed without a new confirmed case.

The outbreak in numbers

As of January 25, 2026, the cumulative total was 19 cases: 14 confirmed, including nine deaths, and five probable cases, all of whom died [s1]. The case fatality rate among confirmed cases was 64.3 percent [s1].

The first known case was an adult from Jinka town who developed symptoms on October 23, 2025, and presented to the general hospital the following day with vomiting, loss of appetite, and abdominal cramps [s1]. The Ministry of Health declared the outbreak on November 14, after the National Reference Laboratory at the Ethiopian Public Health Institute identified Marburg virus in patient samples by molecular testing [s1].

Cases were reported from Jinka, Malle and Dasench woredas in the South Ethiopia Region and from Hawassa in the Sidama Region [s1].

A total of 857 contacts were listed for monitoring — 760 in the South Ethiopia Region and 97 in Sidama — and all had completed 21 days of follow-up as of January 25 [s1]. As of January 5, 3,800 samples had been tested for the virus [s1].

What Marburg is, and why the response looks the way it does

Marburg virus disease is caused by either of two closely related viruses, Marburg virus and Ravn virus [s1]. Across previous outbreaks the case fatality rate has ranged from 24 to 88 percent, and WHO notes it can be lowered with early supportive patient care [s1].

The virus reaches people from fruit bats — Rousettus aegyptiacus — and then spreads between people through direct contact with bodily fluids, contaminated surfaces, or infected materials [s1]. Health care workers, caregivers, and people involved in burial practices are particularly at risk where infection prevention and control measures are not in place [s1].

Symptoms begin abruptly after an incubation period of two to 21 days: high fever, severe headache, malaise, muscle aches, and progressive gastrointestinal symptoms including diarrhoea and vomiting [s1]. In severe cases patients bleed from multiple sites and die of shock and organ failure within a week of symptom onset [s1].

There are no approved treatments or vaccines for Marburg virus disease, although early supportive care improves survival [s1]. Candidate vaccines and therapeutics are under investigation [s1].

That last fact governs everything about the response. With no vaccine to deploy and no antiviral to give, containment is entirely a matter of finding cases, tracing contacts, isolating patients, controlling infection in facilities, and conducting burials safely.

What Ethiopia did

The Ministry of Health established a national taskforce and launched a costed three-month national response plan [s1]. Public health emergency operations centres were activated at national and regional levels with incident management structures [s1].

Two hospitals were designated as treatment centres with dedicated health workers deployed [s1]. Laboratory capacity was strengthened nationally and through a mobile laboratory deployed in Jinka for timely confirmation [s1]. Surveillance and response activities extended to priority points of entry and points of control, alongside community surveillance, contact tracing, and house-to-house visits [s1].

Risk communication teams ran community dialogues, monitored social media to address misinformation, and worked through local networks [s1].

WHO provided technical, operational and financial support across response pillars, supplied testing kits, viral haemorrhagic fever kits and treatment centre modules, and deployed technical experts [s1].

Where this sits historically

Nineteen Marburg outbreaks had previously been reported globally [s1]. The most recent before this one was in Tanzania, between January and March 2025 [s1]. Other countries in the African Region that have reported Marburg outbreaks include Angola, the Democratic Republic of the Congo, Equatorial Guinea, Ghana, Guinea, Kenya, Rwanda, South Africa, and Uganda [s1].

Ethiopia's outbreak was, by the standards of that list, contained relatively quickly: symptom onset in the first known case on October 23, outbreak declared on November 14, last confirmed death on December 14, end declared on January 26 [s1].

What this does and does not tell us

The honest reading is that a first-ever outbreak in a country was detected, laboratory-confirmed, traced, and closed inside roughly three months, with 857 contacts completing follow-up [s1]. That is what a functioning surveillance and response system looks like.

It is not evidence that Marburg has become easier to control. Nineteen cases is a small outbreak, and small outbreaks are contained more often than large ones for reasons that include luck — where the index case sought care, how many people were exposed before recognition, and whether transmission reached a crowded facility.

Two things remain unchanged after this outbreak: there is still no licensed Marburg vaccine or therapeutic, and the reservoir is still present. WHO's account does not identify the source of the initial spillover.

Sources

  1. Disease Outbreak News: Marburg virus disease in EthiopiaWorld Health Organization , January 26, 2026
Related coverage