Tuning daytime and evening light did not improve older adults' sleep
In a 12-person crossover trial, blue-enriched daytime light with reduced evening blue did not cut time spent awake at night, though it nudged a brainwave marker of sleep.
Light alone barely moved young adults' clocks; a combined package did
Two small pilot studies in 18-to-25-year-olds found morning bright light on its own shifted circadian timing little, while adding a timed schedule and evening blue-blockers advanced it about 35 minutes.
Two perinatal sleep studies, one gap: nobody is asking the question
13% of women met criteria for insomnia disorder six weeks after delivery, and only two had been evaluated. In a separate cohort, restless legs in pregnancy tripled the risk of perinatal depression.
Not the oxygen drops: broken sleep tracked with depression, insomnia explained it
In 1,238 people from two community cohorts, apnea severity showed no link to depressive symptoms. Sleep fragmentation did, and that association disappeared once insomnia symptoms entered the model.
Thirty studies imaged the brain before and after CPAP. None of it replicates cleanly.
A systematic review of longitudinal MRI after CPAP for sleep apnoea finds changes reported in every domain and reproducible effects in none — a useful map of what the evidence does not yet show.
A brief insomnia therapy worked during chemotherapy. Light glasses did not.
SleepCARE randomised 219 Australian women receiving chemotherapy for breast cancer to CBT-I, bright light therapy, both, or sleep hygiene. Only CBT-I moved insomnia — and nothing moved fatigue.
Alcohol disrupts REM sleep from about two drinks. It only speeds sleep onset at five.
A meta-analysis of 27 studies found a dose-response pattern that runs against the nightcap logic: the sedative effect needs a high dose, and the REM disruption starts at a low one.
Sleep science barely covers 1.1 billion people. Two studies started filling the gap
Nigerian adults scored well below US and Norwegian comparison samples on a six-dimension sleep health measure. In South Africa, students with backup power were far less likely to report worse sleep during outages.
Sleep trackers went mainstream. The sleep-stage evidence did not follow.
A National Sleep Foundation position statement and a new national survey land on the same problem: a third of US adults track their sleep, and the numbers they trust most are the ones devices measure worst.
Waking in the night is the norm. Struggling to get back to sleep is not.
About a third of adults on two continents wake at least three nights a week. The 7.7% who cannot resume sleep carry almost all of the daytime damage — and the cause is often not what the sleeper thinks.
Irregular sleep is sticky: after six irregular months, it continued 80% of the time
Twenty months of under-mattress sensor data from 95,819 people found that chronic irregularity was common, persistent, and tracked with 46% higher odds of hypertension.
Blue-light glasses: what 17 randomised trials could and could not show
A Cochrane review found they may not reduce eye strain and could not determine whether they help sleep. A separate meta-analysis found small effects. Neither found the evidence anyone assumes exists.
In 7182 Soweto women, the standard sleep questionnaire did not hold together as one score
The Pittsburgh Sleep Quality Index global score is the field's default outcome. Tested in a large South African cohort, its single-factor structure fit poorly and internal consistency was modest.
One insomnia treatment carries a strong recommendation. No sleeping pill does.
Two American guideline bodies grade cognitive behavioural therapy for insomnia as a strong recommendation. Every drug in the sleep-medicine guideline — the ones it endorses and the ones it rejects — came out weak.
Sleep medicine's own guideline suggests clinicians not use melatonin for insomnia
The pooled effect is about seven minutes off the time it takes to fall asleep. The American Academy of Sleep Medicine recommends against it — on evidence it grades as weak in both directions.
Unpredictable shifts track insomnia in Korea roughly twice as strongly as in Europe
Two national survey analyses find schedule unpredictability — not shift work itself — associated with insomnia symptoms, with a dose-response by how much advance notice a worker gets.
Patients with insomnia and apnea saw a bigger blood-pressure drop from CPAP
After four weeks, the comorbid-insomnia group's blood pressure fell 20 points more than the apnea-only group. The finding flips the usual framing of COMISA as simply a worse-outcomes phenotype.
Sleep got worse during Ramadan and mood mostly didn't — in a cohort of 30 Saudi women
Stress peaked during the fasting month and fell afterwards, but depression and anxiety stayed flat. The consistent finding across every phase was that sleep quality tracked mental health.
Digital CBT for insomnia works. Whether people can live with it is a separate question.
A meta-analysis of fully automated programmes found a large effect on insomnia severity. A review of 68 studies found the field has barely measured whether recipients find them acceptable.
NICE reviewed 30 digital mental health tools. The same evidence gaps kept recurring
A cross-sectional analysis of NICE evaluations found 78 supporting studies behind 30 technologies — and consistent holes in comparators, cost of delivery and adverse-event reporting.
Nearly two-thirds of surveyed rural Appalachian adults had clinically significant insomnia
A 327-person survey of economically distressed Eastern Kentucky counties found insomnia prevalence ranged from 44% to 83% depending on income alone.
Sleep apnea plus insomnia tripled mortality risk in a six-year cohort of 2,401 patients
Moderate-to-severe sleep apnea alone roughly doubled all-cause mortality risk. Adding comorbid insomnia to the same patients raised it further — evidence for treating the combination as its own risk category.
Two insomnia drugs alter the sleeping brain differently. Only one tracked with relief.
Reanalyzed EEG data from a phase 3 trial finds lemborexant and zolpidem leave distinct signatures on sleep architecture. Only the slow-oscillation increase predicted less insomnia severity.
Who misuses sedatives to sleep? A US survey finds two different populations, not one
An analysis of nearly 139,000 Americans finds sedative misuse for sleep clusters among both the socially advantaged and the chronically unwell — pointing to two distinct drivers behind the same behavior.
A 2967-adolescent cohort looked for bushfire harm at 24 months and did not find it
Australian teenagers harmed by the Black Summer fires showed no elevated depression, anxiety, distress, insomnia or suicidality two years later. The result runs against a systematic review published months earlier.
Melatonin is the top cause of accidental medicine exposure in under-sevens, a review finds
A systematic review located 19 articles on melatonin in children aged 0 to 6. Trials covered 167 children, all with neurologic conditions. There was no efficacy data for typically developing children.
Sleep apnea plus insomnia raised hypertension risk — but only in one insomnia subtype
In a Pennsylvania cohort followed 7.5 years, the combination carried the highest risk when insomnia came with objectively short sleep. Insomnia with normal sleep duration showed no significant association.
A small insomnia trial asked when in the day a sleeping pill helps — and when it hurts
Standard questionnaires found no daytime difference between suvorexant and placebo. Four-times-daily smartphone prompts found fatigue worse in the morning and better later. The trial had 40 people.
Yoga is recommended for sleep. Against plain stretching, it did nothing extra.
A 240-woman randomised trial compared three months of hatha yoga with a time-matched conditioning programme. On every sleep measure, the two groups moved together.
In an Ecuadorian survey, stress and anxiety predicted insomnia — demographics did not
Age, sex, employment and socioeconomic level together explained under 1% of variance in insomnia severity. Perceived stress and generalised anxiety explained close to a third.
A doctor's recommendation is not substantiation, and US ad rules say so
FTC staff guidance is explicit: an honest testimonial is not evidence. The advertiser still needs competent and reliable science for the claim the testimonial implies.
Caffeine cost about 35 minutes of sleep in pooled lab trials
A meta-analysis of 22 crossover trials with overnight polysomnography found consistent losses in total sleep time and efficiency. The age and dose subgroup differences everyone wants were not statistically significant.
Sleep hygiene advice works better as a companion than as a treatment
Forty-two trials show sleep-hygiene education helps a little and helps less than the alternatives. The sleep-medicine guideline suggests clinicians not use it on its own.
Night-time insomnia predicted no extra heart risk without daytime symptoms
In 24,223 Swedish workers followed to 2018, insomnia and long sleep raised cardiovascular risk only when accompanied by daytime impairment — and rising sleep duration preceded disease.
Patients said group sleep restriction was hard, and the group is why it worked
Fourteen Swedish primary care patients were interviewed alongside a trial of nurse-led group sleep restriction therapy. Depression and life circumstances were what got in the way.
Insomnia flagged a disputed parasomnia in Ukrainian combatants
In 99 men hospitalised for stress-related disorders, roughly four in five met probable criteria for trauma-associated sleep disorder — a condition that is not yet a recognised diagnosis.
A tuned LLM outscored experts on sleep and fitness exams. Then came the hard part
Google's PH-LLM beat sampled human experts on multiple-choice tests but only matched them on real cases. A new reporting checklist published the same month explains why such claims are hard to compare.
An orexin-2 blocker beat zolpidem on night 13 in a dose-finding insomnia trial
Seltorexant held its effect over two weeks while zolpidem's faded, in a 364-person study run in 2017-2019 and published only now. The delay is disclosed in the paper itself.
An automated internet CBT-I programme held its gains in older adults at 12 months
In 311 adults aged 55 to 95, remission rates were 40% and 51% in the two intervention arms at one year, against 16% for online patient education. Adding human support helped a little.
A global insomnia estimate built from 18 studies and 31 countries
Applying prevalence figures to UN population data yields 852 million adults with insomnia. Only 31 of 237 countries had a usable national estimate of their own.
A ten-society guideline on tapering benzodiazepines, and data on who is starting them
The guidance is built on one negative instruction: do not stop abruptly in patients likely to be physically dependent. Hong Kong records show the sharpest prescribing rise in 18-to-25-year-olds.