For how we live.
In 415,000 New Jersey births, infants of mothers who screened positive for depression died before age one at more than three times the rate, an association steady across race, income and preterm birth.
A review by the country's Public Health Authority credits enforcement and awareness campaigns for falls in crashes, deaths and injuries from 2013 to 2023 — while naming what still holds the Vision 2030 target back.
The famous cigarette comparison is a communications gloss on a robust but observational finding: people with stronger social ties are markedly more likely to survive follow-up.
In half a million people, weaker grip tracked with higher mortality — a strong marker. But it reads out whole-body strength and health, not a number you move by training your hands.
A 1.5-million-person records study reports lower mortality with GLP-1 drugs than with SGLT2 inhibitors, and the largest absolute gains in people with serious mental illness. The design cannot prove it.
Two large cohorts link purpose in life to lower mortality and lower Alzheimer's risk. Whether purpose protects health, or health sustains purpose, is what the studies cannot fully separate.
More than 2,700 people died in England and Wales during the May and June heatwaves. An attribution study assigns roughly 42% of those deaths to warming.
Emulating a trial inside Veterans Health Administration records, researchers estimated adjusted mortality risk ratios of 0.90 to 0.84 for starting continuous glucose monitoring in older-onset type 1 diabetes.
A sibling-controlled cohort of 1.1 million men, a genetic analysis of 712 traits and a UK Biobank study of fitness change converge — and they agree on where the exception is.
Chronic granulomatous disease is usually X-linked in Western cohorts. A multicentre Middle East and North Africa registry found the opposite pattern, alongside late diagnosis and a median survival of 8.5 years.
Across 107 cohort studies and 4.8 million people, the protective effect of moderate drinking disappeared once the comparison group stopped including people who had quit because they were ill.
Researchers modelled 854 European cities under the climate that exists and the one that would have existed without human warming. The attributable share rose from 45% to 64%.
A harmonised meta-analysis of more than a million people found the association between sitting time and death disappeared in the most active quarter. In the least active, it did not disappear at all.
In 390,124 US adults followed up to 27 years, daily multivitamin use showed no mortality benefit. Randomised trials within COSMOS found a real but modest effect on memory, and none on physical function.
A dose-response meta-analysis of 94 cohorts and more than 30 million people found the steepest part of the curve sits between zero and the recommended weekly dose, with small and uncertain gains above double it.
A 2025 meta-analysis of 57 studies found the mortality curve bending at about 7,000 steps a day. The 10,000 figure traces to the trade name of a Japanese step counter sold in 1965.
A registry study spanning 4.9 million people separates where the most deaths occur from where the inequality is largest. Heart disease and lung disease give different answers.
Maricopa County runs some of the most detailed heat mortality surveillance in the US. A distributed lag model applied to the same five years put the toll far higher — and the gap is the method, not a scandal.
A registered report fit identical models to 11 longitudinal studies covering 175,070 people. The subjective feeling carried the signal; the objective count of social contacts largely did not.
Three cohorts, 147,374 people, 30 years and 35,798 deaths. The dose-response curve flattened above 120 minutes per week, and the cancer signal appeared at the low end, not the high end.
A national case-crossover study of 236,260 chronic kidney disease deaths finds women, over-65s and people in cooler regions most affected — and projects the burden nearly quadrupling by the 2090s.
An analysis of nearly 30 years of confirmed heat deaths finds many occurred well under standard alert thresholds, and that humidity-based measures may track risk more consistently.
The comparison group matters: against veterans with unspecified narcolepsy diagnoses, the mortality gap widened to 140% higher odds. The study can't yet say what's driving the excess deaths.
Moderate-to-severe sleep apnea alone roughly doubled all-cause mortality risk. Adding comorbid insomnia to the same patients raised it further — evidence for treating the combination as its own risk category.
A meta-analysis spanning two decades of research found extreme cold carried a higher relative risk of death than extreme heat or heatwaves — even as warming shifts public attention toward summer temperatures.
A 14-year national analysis finds temperature-related death rates rising fastest in the group that started highest — and the same pattern in cold deaths, which fell for everyone else.
A wavier jet stream delivered severe cold to three continents in a month that was 1.47°C above pre-industrial globally. Two new studies quantify what cold still does to mortality.
A nationwide register study found a hazard ratio of 0.96 for all-cause death among users of menopausal hormone therapy. The raw death rate in users was higher — which is the part worth understanding.
The Lancet Global Health paper that produced this month's headline number also produced a larger one: 22.6 million additional deaths by 2030 if defunding deepens. The distinction matters more than the figure.
A December survey found getting stronger is the leading 2026 health goal. The best meta-analysis of muscle-strengthening and mortality finds a benefit that plateaus at around 30 to 60 minutes a week.
Berkeley researchers followed older Californians for a decade. Cumulative smoke exposure predicted death better than the number of smoke days did — which is not how air quality is usually reported.
Across 11 surveillance sites in sub-Saharan Africa, nighttime heatwave mortality risk rose between 2005-2010 and 2011-2015 — the opposite of the adaptation trend reported in wealthy countries.
A meta-regression across 28 countries put pooled prevalence near 4-5% and standardised mortality ratios between 1.8 and 4.7, in a condition the Global Burden of Disease study does not count.
Researchers tested heat-mortality forecasts against the European summers of 2022 and 2023. The skill pattern is not the one a warning system designer would have guessed.
A new GBD analysis puts sepsis-related deaths at 21.4 million, roughly double the 11.0 million estimated for 2017 — a change driven partly by COVID-19 and partly by a different method.
A 47-prefecture analysis of a decade of heatstroke mortality finds the alert level set at 33C misses almost all of the deaths a warning could plausibly prevent. About 31C would halve them.
Age-standardised disability-adjusted life-years fell 12.6% since 2010, but the raw total rose 6.1% to 2.80 billion. Anxiety, depression and diabetes rose fastest even after adjusting for ageing.
A global analysis separates exposure inequality from mortality inequality and finds they run in opposite directions between countries, and sometimes within them.
One projects 71,420 US deaths a year from wildfire smoke by 2050. The other projects 1.4 million globally by the end of the century, with Africa's burden rising elevenfold. Both rest on modelled chains, not observations.
A 50-year attribution study separates two trends that usually get modelled as one: rising temperatures and a population that has become less likely to die in them.
A nine-year case time-series across every municipality finds both ends of the temperature range raise mortality risk on a Caribbean island, with the burden spread unevenly across towns.
A pan-tropical analysis links deforestation-driven local warming to about 28,000 heat-related deaths a year, with Southeast Asia carrying the highest rate.
A 15-city study found a pooled relative risk of exactly 1.00 for heat warnings. Adjusting for green space, population and density turned it into 0.85. Both numbers are in the same paper.
About 1,009 deaths a year were attributable to heatwaves in 2016-2019. Queensland and New South Wales carried rates more than three times Western Australia's.