For how we live.
A bird-flu virus from British Columbia poultry carried the H275Y mutation that blunts Tamiflu and peramivir. In the lab it stayed vulnerable to zanamivir and baloxavir — and was less virulent in mice.
The honest position is two things at once: the current risk to the general public is low, and the reason it is watched so closely is that its worst-case potential is high. The gap between the two is the whole story.
An 8-year-old boy had brain inflammation with no respiratory symptoms. Every respiratory, blood and rectal sample tested negative; the virus was in his cerebrospinal fluid alone.
WHO has logged 11 laboratory-confirmed human A(H5N1) infections in Cambodia between 1 January and 1 July, including six deaths. Every case had handled or culled sick poultry.