For how we live.
A four-branch surveillance study in children found 2024 Mycoplasma pneumoniae incidence of 546 per 100,000, and genome sequencing showed four new subclades had replaced older lineages by mid-2024.
A prespecified analysis of 131,276 older adults found RSVpreF cut RSV hospitalisations overall. In the immunosuppressed, baseline risk was nine times higher — but the subgroup was too small to prove it helped them.
A 28-year-old technician at a plague research institute in Irkutsk died on 2 October. WHO rates the risk low in Russia and very low in Europe, but has asked Russian authorities to clarify the cause of her pneumonia.
A nationwide Brazilian cohort of 4.1 million children found that babies exposed to Zika in the womb but without congenital Zika syndrome had the same pneumonia-hospitalisation risk as unexposed children.
Across 41 hospitals in 19 Asian countries, ACORN-HAI found 73.7% of severe bloodstream and ventilator infections were drug-resistant, and 37.7% of those patients died within 28 days.
A study of 46 pathogens attributes about 66,400 child deaths in 2023 to Streptococcus pneumoniae across G20 countries, with the heaviest load falling on India, South Africa and Indonesia.
A cohort at Kilifi County Hospital found RSV pneumonia killed 2.4% of admitted infants across 25 seasons, with no decline; severe undernutrition and congenital heart disease marked the highest risk.
A six-month regimen for drug-resistant tuberculosis matched the standard of care in South Africa. Four days of antibiotics matched eight in African children hospitalised with severe pneumonia.
A meta-analysis of more than 155,000 children finds mortality is elevated even at oxygen saturations of 90–94%, above the threshold at which WHO advises hospital oxygen.
Two pragmatic randomised trials and a Medicare nursing home cohort landed in the same week. Together they show real protection against hospitalisation and a durability question nobody has answered.
New conjugate vaccines replaced a confusing two-shot sequence with a single dose. The efficacy evidence is solid for the older conjugate; the newest ones ride on immune-response data, not their own outcome trials.
Two February papers put respiratory virus activity into the models. One finds pollution effects amplified at peak influenza; the other finds them attenuated when rhinovirus is high.
A Lancet study across 547,000 adults and 925 infectious diseases finds obesity raises the risk of severe infection across almost every pathogen type. The global estimate rests on modelling, not on the cohorts themselves.
Nearly a million conscripts followed for three decades: obesity carried a 3.1-fold hazard for sepsis, and high cardiorespiratory fitness was associated with a 42% lower risk of dying from bacterial infection.
Deaths during combined heat and ozone days in Hong Kong, preterm births projected across Chinese cities to 2100, and a seasonal flip in Japan's ambulance demand from winter to summer.