For how we live.
Ginger's strongest evidence is unglamorous: it eases nausea in pregnancy and during chemotherapy, and modestly relieves osteoarthritis pain. The trials are small and the quality is moderate at best.
Two blinded randomised trials found magnetic wrist straps and copper bracelets worked no better than dummy versions for arthritis pain. The reported relief looks like a placebo effect.
Topical diclofenac and ketoprofen beat their carrier gels for knee osteoarthritis pain, with about 60% of users reporting much less pain. A large network meta-analysis now rates topical diclofenac a first-line option.
Studies going back decades find no link between habitual knuckle cracking and hand arthritis. One doctor cracked a single hand for a lifetime to prove it — and got arthritis in neither.
Small trials suggest curcumin can modestly reduce arthritis pain, sometimes on par with painkillers — but the evidence is thin, and turmeric supplements are linked to a rising number of serious liver injuries.
A matched study compared recreational runners, non-runners and adults with obesity, one triplet at a time. The first two groups were indistinguishable on structure and function. The third was not.
A Lancet review triangulates the evidence linking adiposity to multisystem disease and finds robust trial support in a short list — while an expert panel argues the drugs must be lifelong.
The gap between those two numbers is the whole argument. An individual-patient meta-analysis of 20,827 people found real effects on both comparisons, and found that the choice of sham changed the answer.
RACER-Knee masked patients with sham incisions and found a Forgotten Joint Score difference of −1.5 points at 12 months (P=0.62) — while the robotic operation cost more.
The first randomised trial to pit surgery against the natural course of big-toe arthritis found fusion cut walking pain to 1.3 on a 10-point scale at one year, versus 5.7 with watchful waiting.
The WISeR model starts on 1 January in six states. The contractors running it are paid out of the savings their determinations produce — the design feature doctors keep pointing at.
A small prospective cohort followed 62 reconstructions for a quarter century. The graft type made no difference, and the uninjured comparison group dropped out of sport faster.