For how we live.
Hospital admissions for food anaphylaxis in the UK rose 5.7% a year for two decades while the case fatality rate fell. The treatment recommendations have almost no randomised evidence behind them.
A European allergy task force concluded the antibody these tests detect is a marker of tolerance, not hypersensitivity. Meanwhile 19% of US adults believe they have a food allergy and about 10.8% have one.
The LEAP trial cut peanut allergy in high-risk infants from 13.7% to 1.9%. A second trial found the benefit real but harder to achieve — and only in children who actually ate the food.
The LEAP trial reversed a generation of avoidance advice. A second trial run in the general population missed its primary endpoint, and the distance between those two results is the part usually left out.