Only about 3% of children follow the 'atopic march' from eczema to asthma to hay fever
Two birth cohorts totalling 9,801 children were sorted into eight developmental patterns. The classic progression was one of them, and one of the smallest.
The strongest breastfeeding evidence is more modest than the slogan suggests
A large randomised promotion trial and sibling studies find some real benefits in infancy — fewer gut infections, less eczema — but the sweeping long-term advantages shrink once confounding is accounted for.
Feeding infants peanut early prevents allergy. The old advice to avoid it backfired.
The LEAP trial cut peanut allergy in high-risk infants from 13.7% to 1.9%. A second trial found the benefit real but harder to achieve — and only in children who actually ate the food.
Feeding peanut to high-risk infants cut peanut allergy from 13.7% to 1.9%
The LEAP trial reversed a generation of avoidance advice. A second trial run in the general population missed its primary endpoint, and the distance between those two results is the part usually left out.