For how we live.
Tranexamic acid cut postpartum haemorrhage in placenta praevia. Dapagliflozin nearly halved acute kidney injury after cardiac surgery. The effect sizes are very different, and so is how much to trust them.
A 293-woman Dutch trial found more women reported improvement at 12 months with perioperative oestriol cream than placebo. Anatomical success, surgical success and reintervention were unchanged.
In 2,286 patients with sleep apnea undergoing major surgery, a measure of how deeply and how long oxygen fell — not the apnea-hypopnea index — tracked 30-day cardiovascular events and death.
A network meta-analysis of 41,084 surgical patients over 60 ranked 52 drug interventions. Dexmedetomidine held up after high-risk trials were excluded; almost nothing changed length of stay or mortality.
A small prospective cohort followed 62 reconstructions for a quarter century. The graft type made no difference, and the uninjured comparison group dropped out of sport faster.