Stem-cell exhaustion, read in the blood: what clonal haematopoiesis reveals
As blood stem cells age, mutant clones take over. By the eighth decade this shows up in about one person in ten — and it tracks with higher mortality and heart disease.
GDF11 was called young blood's rejuvenation factor. A rival lab could not reproduce it.
Mouse studies claimed one circulating protein reversed ageing of the heart, muscle and brain. A second team found the muscle effect ran the opposite way — and no human trial has ever tested it.
Why do we get goosebumps?
The reflex that stands body hair on end in the cold or at a stirring piece of music is largely a leftover from furrier ancestors — but new work shows the same wiring quietly keeps hair able to regrow.
'Young blood' for ageing: what parabiosis and plasma exchange actually show
Infusing plasma from young donors is sold as rejuvenation. The mouse work suggests diluting old blood may matter more than adding young blood — and regulators warn the paid infusions have no proven benefit.
NIH cut off fetal tissue funding and paused its embryonic stem cell registry
Two notices, one day apart, end one line of federally funded research and freeze another pending review. NIH is now asking scientists which experiments could not be done without embryonic stem cells.