For how we live.
A 67-study meta-regression found muscle growth keeps rising with weekly sets, with diminishing returns. A 15-site trial of 297 lifters found stretch-position partial reps produced effects close to zero versus full range.
Pooled randomised data show incretin drugs shed lean mass in about the same proportion as lifestyle weight loss. The evidence gap is people who train seriously, and it has not been filled.
A meta-analysis of 26 trials found creatine raises serum creatinine without markers of kidney injury. Weeks earlier, a Nature Communications paper reported that supplementation promoted metastasis in mice.
A review screening 14,125 articles found evidence neither for nor against morning or evening training — only that testing and training at the same hour helps. Evening sessions may cost some sleep continuity.
Sarcopenia got a formal definition and diagnostic cut-offs. The clinical guidelines that followed back resistance exercise strongly — and are far more cautious about protein powders, vitamin D and drugs.
A 2026 meta-analysis of 86 randomised trials found body mass, waist circumference and maximal oxygen uptake still better than baseline more than six months after training stopped. Not everything held.
A meta-regression of 23 hypertrophy studies found total intake the strongest predictor and no timing effect after adjustment. A later network meta-analysis of 116 trials still favours post-exercise, narrowly.
Three cohorts, 147,374 people, 30 years and 35,798 deaths. The dose-response curve flattened above 120 minutes per week, and the cancer signal appeared at the low end, not the high end.
A panel of fitness and healthcare professionals reached full agreement on 27 medical conditions that call for caution — or, in two cases, avoidance — before starting resistance training.
A meta-analysis of eleven depression trials found an average effect below the threshold for clinical importance, with signs of bias favouring creatine. A separate review found no change in kidney filtration.
A meta-analysis of 20 trials found a two-kilogram gain in one-rep max and no effect on bone density. A small crossover trial found functional strength gains largely independent of muscle mass.