In 643 Indian infants, an adjuvanted dose-sparing IPV with about a quarter of the antigen was non-inferior to standard IPV across all three poliovirus types — a possible answer to supply strain.
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WHO's Emergency Committee extended the public health emergency for three more months. Wild poliovirus cases dropped from 99 to 40, while vaccine-derived strains spread to two new countries.
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The year-end immunization summary reports 88% fewer measles deaths since 2000, malaria vaccine in 24 African countries, and 25 years without wild polio in the Western Pacific.
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Nine genetically linked virus isolates from seven environmental sites triggered the declaration. Sequencing traced the lineage back to a paralysis case reported in December 2024.
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Two healthy children in Lae tested positive for cVDPV2 genetically linked to an Indonesian outbreak, in a country where coverage for a third oral polio dose was 44% in 2024.
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