Stargardt disease, the most common inherited macular dystrophy, has no approved treatment. In the 50-patient TEASE-1 trial, gildeuretinol slowed atrophic lesion growth by a fraction of a millimetre a year.
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In South Kivu, ophthalmologists examined 310 patients with confirmed clade Ib mpox at four time points. Periorbital lesions and severe acute malnutrition tripled the risk of ocular involvement.
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EXPLAINERThree of the four Yamanaka factors, delivered to one eye and switched on with an antibiotic for eight weeks. The mouse data are striking; the trial is a safety study and will not measure ageing.
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WHAT THE STUDY ACTUALLY SAYSThe trials that made eye vitamins a standard recommendation enrolled only people who already had substantial disease. In AREDS2, neither omega-3 nor lutein beat placebo on the primary endpoint.
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ANALYSISEyeFM was tested as an assistant to 16 ophthalmologists screening 668 high-risk patients in China. Patients in the AI arm also followed referral advice more often.
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ANALYSISOff-the-shelf features from two published models matched retinal scans to the right patient 78% to 86% of the time. Fine-tuned for the task, one model reached 99.5% on OCT.
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