For how we live.
Omega-3 supplements are widely recommended for dry eye, but the largest randomised trial found them no better than an olive-oil placebo. A Cochrane review leaves the case uncertain at best.
Large randomised trials mostly find no cardiovascular benefit from ordinary fish-oil capsules. One high-dose prescription drug is the striking exception, and the case for brain protection is weak.
A large Cochrane review found fish-oil supplements cut early preterm birth substantially. The biggest single trial since found no effect at all — a genuine split the marketing skips over.
The DO-HEALTH sub-study is the first randomised evidence that a supplement can nudge DNA-methylation ageing clocks. The effect was tiny, and the parent trial found no benefit on health outcomes that matter.
PISCES randomised 1,228 haemodialysis patients in Canada and Australia. The headline hazard ratio of 0.57 counts every event, not just the first — and that choice explains part of the gap.
October brought pooled analyses of ginger and of marine omega-3s. Both report significant effects on blood markers. Neither measured whether anyone got healthier.