Does sweating more mean you're burning more fat?
No. Sweat is how the body sheds heat, not fat. The weight lost in a hot workout or a sauna is water, and it comes back the moment you rehydrate.
Do fat burners actually work?
Barely, and some carry real risk. Caffeine has a small, measurable effect; the other headline 'thermogenic' ingredients mostly don't, and high-dose green tea extract has caused liver injury.
Is 'starvation mode' real? Your metabolism slows, but it can't stall fat loss
Losing weight lowers resting metabolism and keeps it low — Biggest Loser contestants ran hundreds of calories below baseline six years on. But that brake slows loss; it does not store fat.
Does fasted cardio burn more fat? What the trials actually show
Exercising before breakfast shifts which fuel your body uses during the session, but pooled trials find no meaningful edge for weight or body-fat loss over the same workout done fed.
Why you regain weight after dieting: the body defends the fat you lost
Six years after 'The Biggest Loser', contestants had regained most of the weight — and their resting metabolism was still running 500 calories a day slower than expected. The diet triggers a defence that outlasts it.
Do cheat days work? Planned diet breaks have better evidence
An unplanned cheat day can erase a week's calorie deficit and has no trial support. Structured diet breaks are different — one trial found they improved weight loss, though another found no body-composition edge.
Does building muscle really boost your metabolism? What the numbers show
A kilogram of muscle burns about 13 calories a day at rest — far less than the fitness-marketing figure implies. But resistance training does nudge resting metabolism up, by roughly 96 calories a day in a meta-analysis.
Does your metabolism really slow down in your 30s and 40s?
A large study of energy use across the lifespan found it holds steady from age 20 to 60, once body size is accounted for. The midlife metabolic slump is mostly a myth; the decline comes later.
Removing one mitochondrial protein protected mice from diet-induced obesity
Mice lacking the chaperone GRPEL2 stayed leaner on a high-fat diet and kept better insulin sensitivity — an early mechanistic finding, not a treatment, and so far only in mice.
The first oral GLP-1 is approved. The needle was never the only barrier.
Orforglipron removes the injection from weight-loss medicine — a real change for people who refused one. Supply, cost, and coverage are the harder problems it does not solve.
A sugar-processing defect in the brain, and a supplement that made it worse in mice
University of Florida researchers identify excess glycan production as a driver of Alzheimer's pathology, and find oral glucosamine worsened cognition in mice and tracked with faster decline.
Six months of intermittent fasting: 8% weight loss, better lipids, and not much else
The trial's own primary outcome — inflammation — was flat. What the new analysis adds is a molecular account of why the fat loss did not translate into the benefits fasting is sold on.