ANALYSISUS POINTER randomised 2,111 at-risk older adults to two lifestyle programmes. The structured version beat the self-guided one on cognition — but by a modest margin, and there was no do-nothing group to compare against.
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WHAT THE STUDY ACTUALLY SAYSA 140-woman randomised trial found diet-and-exercise coaching, added to hormonal treatment, cut some pain scores more than usual care — but the differences were small and menstrual pain did not budge.
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EXPLAINERPrediabetes is a high-risk state, not a diagnosis of diabetes. In the trial that defined the field, lifestyle change cut progression by 58 percent — and returning to normal glucose carried a benefit of its own.
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WHAT THE STUDY ACTUALLY SAYSIn a 618-person randomized trial, 27.8% of the intervention group met the sustained-remission endpoint at 24 months against 21.2% of comparators. The confidence interval nearly touches no effect.
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WHAT THE STUDY ACTUALLY SAYSAn analysis of 104 trials found a 10 to 20 percent reduction under some diagnostic criteria and none under UK criteria. A separate review found a GDM diagnosis is not associated with more stillbirths.
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