For how we live.
In 1,095 high-risk abdominal-surgery patients, targeting each person's own cardiac index during the operation left the rate of major complications essentially unchanged — 44.3% versus 46.9%.
Gout affects about one in twenty American men, driven by high uric acid. Guidelines and randomised trials back long-term urate-lowering to a target below 6 mg/dL, yet only a third of patients receive it.
Fever is often the only clue in a young child, a properly collected urine sample confirms it, and most cases clear on a short antibiotic course. Preventive antibiotics cut recurrences but breed resistant bugs.
LITESPARK-022 cut the risk of recurrence by 28% when belzutifan was added to pembrolizumab after surgery. Survival was no different, and severe side effects nearly doubled.
Kidney disease is usually silent until it is advanced, and most of it traces to diabetes and high blood pressure. Controlling those two, and getting tested, is the highest-yield protection — not kidney superfoods.
A meta-analysis of 90,000 people found these diabetes-origin drugs reduced kidney disease progression by 37% and cardiovascular events by 23%, and the benefit was similar in people who did not have diabetes.
High urate levels track with worsening kidney disease, so treating them seemed a logical way to slow it. Two trials that lowered urate with allopurinol found the kidneys declined at the same rate anyway.
In people who already have kidney disease, cutting salt reduced albuminuria by about 36% and lowered blood pressure. High salt also blunts standard kidney-protecting drugs — though long-term outcome trials are missing.
Low fluid intake is a genuine, well-evidenced stone risk factor. Increasing fluid to produce plenty of urine is the single best-supported way to prevent another stone — better established than any diet tweak.
The fear that a high-protein diet damages normal kidneys is not supported by the trial evidence. Protein restriction is a therapy studied in people who already have kidney disease — a different question entirely.
Creatinine is muscle waste your kidneys clear; eGFR is an estimate of filtering capacity built from it. A single reading is a snapshot, not a diagnosis — and the equations have limits worth knowing.
Observational studies link higher water intake to healthier kidneys. When a randomised trial coached people with kidney disease to drink more, their filtration fell at the same rate as the control group.
Across studies, current NSAID use was tied to about a 73% higher odds of acute kidney injury, more in older people and those with existing kidney disease. The combination with two blood-pressure drugs is the real hazard.
A study of 19,539 patients echoed the randomised CONVINCE trial — but it was observational, and several of its authors work for the dialysis company that owns the data.
There is no trial showing a cleanse product improves kidney function, which already filters blood continuously. One class of herbal kidney remedy is a proven cause of kidney failure and cancer.
In the FIND-CKD trial, non-diabetic patients on finerenone lost kidney function at 3.3 versus 4.0 ml/min/1.73 m² a year — a small edge that extends a diabetes drug to a new group.