WHAT THE STUDY ACTUALLY SAYSIn the PROGRESS trial, 744 patients with moderate aortic stenosis and an at-risk feature got early TAVR or clinical surveillance. Death or a heart-failure event at two years fell from 23.9% to 16.7%.
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WHAT THE STUDY ACTUALLY SAYSIn the P4 trial, 1105 patients having coronary stents placed were randomised to planning by CT angiography or by intravascular ultrasound. Target-vessel failure at one year was 4.1% versus 4.6% — non-inferior.
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WHAT THE STUDY ACTUALLY SAYSA Swiss investigator-led trial tested whether isolating the back wall of the left atrium on top of pulsed-field pulmonary vein isolation cuts arrhythmia recurrence. The primary answer was no.
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WHAT THE STUDY ACTUALLY SAYSIn 264 patients in China, the device maker's trial reported clinical worsening in 25.7% versus 51.5% on medical therapy alone (HR 0.49) — but no sham procedure blinded patients.
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WHAT THE STUDY ACTUALLY SAYSPRAGUE-26 randomised 558 patients across 11 Czech hospitals. The seven-day composite fell from 6.8% to 0.7%, driven by cardiorespiratory collapse, with no clear bleeding penalty.
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