For how we live.
In the SNAP platform trial, cefazolin was non-inferior to flucloxacillin or cloxacillin for 90-day survival in methicillin-susceptible S. aureus bacteraemia, and caused notably less acute kidney injury.
In the SOLARIO trial, patients who got local antibiotics at surgery did no worse on a short systemic course than a long one, and reported far fewer side effects. The comparison was independently funded.
Urinary infections in men were long treated as automatically complicated. A randomised trial found seven days of antibiotics non-inferior to fourteen, and guidelines say not to treat urine that causes no symptoms.
In the TESEO trial, benznidazole for 30 days matched the 60-day standard for clearing the parasite and caused fewer side effects, pointing to a gentler regimen for a neglected disease.
An observational study across four DR Congo outbreak sites estimates that a third of positive mpox PCR results reflect environmental viral DNA, not infection — and that a stricter cutoff fixes most of it.
A study of 46 pathogens attributes about 66,400 child deaths in 2023 to Streptococcus pneumoniae across G20 countries, with the heaviest load falling on India, South Africa and Indonesia.
England's scarlet fever rate tripled after 2014 and a more toxigenic strep A lineage emerged, culminating in the deadly 2022 wave of invasive infections in children.
Around 60–70% of infants carry Clostridioides difficile without illness. A Science study finds its toxins remodel the newborn gut in mice — but the direct human evidence is still limited to cells and biopsies.
The childhood infection clears on its own in most children and has no specific antiviral. The evidence that matters is about the rare severe case — and where it happens.
A systematic review of the Syrian crisis and infectious disease in Lebanon names overcrowding, poor sanitation and blocked healthcare access — not the presence of refugees themselves — as the reported drivers.
A narrative review synthesising WHO, UNRWA and Gaza health-ministry field data reports the re-emergence of hepatitis A and poliovirus, over 200,000 diarrhoeal cases, and drug-resistant hospital pathogens.
Vibrio vulnificus wound infections rose eightfold along the Eastern US between 1988 and 2018, and a 2026 model projects recreational-water infection risk climbing up to a thousandfold by 2100.
In the LATITUDE trial, monthly cabotegravir–rilpivirine injections cut regimen failure to 22.8% from 41.2% on oral therapy among people with a history of missed doses, prompting an early stop.
A Lancet study across 547,000 adults and 925 infectious diseases finds obesity raises the risk of severe infection across almost every pathogen type. The global estimate rests on modelling, not on the cohorts themselves.