For how we live.
A CDC-journal study found the human-adapted subtype IfA12G1R5 rose to 67.5% of genotyped cases in 2023 while the long-dominant IbA10G2 fell from 79.7% to 1.6%, as COVID-era measures reshaped transmission.
Guangdong recorded 25,335 local cases in 2025 — 98% of everything China has ever reported. Genomic analysis finds every Chinese outbreak lineage matching a recent import.
A 23-year genetic-network analysis of 5,094 cases identified 107 molecular super-spreaders, mostly men aged 50-69, with 94.4% living within 2 km of major transport routes.
WHO reports two cases of a monkeypox virus carrying genetic material from both clade Ib and clade IIb. The finding that matters for surveillance is that clade differentiation PCR missed it both times.
Negotiators on the Pandemic Agreement's pathogen-sharing annex met January 20–22 and reported emerging consensus on parts of the system. The deadline is the World Health Assembly in May.