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Ervebo was licensed against Zaire ebolavirus. WHO says it is not known whether it protects against Bundibugyo virus in humans — which is why a trial is running alongside the wider rollout.
WHO's latest update records 1,129 more confirmed cases in twelve days and a case fatality ratio of 48.1%. Transmission is now confined to Congo, across 60 health zones in six provinces.
In South Kivu, ophthalmologists examined 310 patients with confirmed clade Ib mpox at four time points. Periorbital lesions and severe acute malnutrition tripled the risk of ocular involvement.
The Bundibugyo virus epidemic is now the largest Ebola outbreak in Congo's history. WHO's emergency committee met again this week; MSF says the response still isn't reaching people fast enough.
Two months after the emergency declaration, confirmed cases in DRC have passed 2,100 and spread to 46 health zones. There is still no approved vaccine or treatment — but patients are now being enrolled in one.
Five weeks into the Bundibugyo virus emergency, WHO says some new cases reflect transmission that had gone undetected for weeks — a sign the outbreak may be larger than the count shows.
WHO declared a public health emergency of international concern on 17 May. By early June, confirmed cases had climbed past 500 and Africa CDC put a price tag on the continental response: $518 million.
Eight confirmed cases, 246 suspected, and 80 suspected deaths in eastern DRC were enough for the Director-General to invoke his highest level of alarm — before convening the emergency committee that usually comes first.
The Bulape outbreak in Kasai Province ended 88 days after it was declared, with a case fatality ratio above 70% and nearly 48,000 people vaccinated.
Sequencing points to a fresh spillover from wildlife rather than a resurgence of the province's earlier outbreaks. Four of the dead are health-care workers.