EXPLAINERFace, arm, speech, time is the message that saves lives. But in one US stroke centre 14% of ischaemic strokes had no FAST sign at all — and every minute of delay costs an estimated 1.9 million neurons.
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WHAT THE STUDY ACTUALLY SAYSThe system sorts feverish under-5s into red, amber and green. Validation studies find it misses serious illness and over-refers the well — a prompt, not a reliable test.
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WHAT THE STUDY ACTUALLY SAYSSubstantial, sustained weight loss can return blood sugar to the normal range without drugs in some people diagnosed recently. It is real, it is not a cure, and it fades as the weight comes back.
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ANALYSISThe ESC released updated heart failure guidance plus first-ever guidelines on cardiac rehabilitation and on cardiovascular disease with chronic kidney disease. All three sit behind a paywall.
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ANALYSISA system called Quicker writes clinical guideline recommendations through a GRADE workflow. A Matters Arising and its reply, published the same day, map what still has to be built around it.
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EXPLAINERWHO's ICD-11 lists burn-out, yet places it among reasons people contact health services, not among illnesses. It is defined strictly as a workplace phenomenon, which shapes who should be assessing it and how.
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EXPLAINERIts guideline says antipyretics should be considered when a feverish child appears distressed, not to lower a temperature. In critically ill adults, paracetamol for fever changed nothing.
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EXPLAINERUS and UK guidelines converge: a brief seizure during a fever in a young child rarely needs scans or blood tests, and paracetamol and ibuprofen do not stop them recurring.
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EXPLAINERIts 2024 guideline also advises against routine blood testing for vitamin D, on the grounds that no trial evidence supports it. The largest randomised trial found no effect on cancer, heart disease or fractures.
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EXPLAINERAmerican guidelines call 130/80 stage 1 hypertension. European ones call the same reading elevated blood pressure and not yet disease. The measurement did not change. The label did.
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