For how we live.
In a 12-month trial of 89 older adults with vascular cognitive impairment, strength training did not slow whole-brain white-matter lesions overall — but it did in women, and in two specific brain regions.
In 20 healthy young adults, closed-loop acoustic stimulation of slow waves boosted word recall, and the benefit tracked a shift in how sleep spindles nested within slow oscillations.
In LatAm-FINGERS, 1,065 at-risk older adults across 11 countries did better on cognitive tests with structured coaching than with flexible health advice over two years. The gap was small.
The idea that sleep flushes toxins from the brain rests largely on mouse experiments. A 2024 study using the same animal measured the opposite direction, and none of it has been shown in humans.
A cohort with serial MRI and autopsy data found earlier menopause tracked faster cognitive decline and white matter damage. The per-year coefficients are very small.
Imaging finds smaller brain volumes from as little as one to two daily drinks. Long-run dementia studies show a U-shape, with abstainers also at higher risk — a pattern that is easy to misread.
747 postmenopausal women were tested; 182 were scanned. Gray matter volume partially mediated the link between menopause age and cognition — in a cross-sectional design that cannot establish direction.
Heading rates rise about 13% with each age group from under-9s to seniors. Unintended head impacts during headers were rare — 31 in 687 matches — and most common in adults.