For how we live.
A final order published 5 November classifies wearable devices that apply targeted mechanical vibration to the skeleton to reduce loss of bone strength or density, setting the evidence such products must meet.
Regeneron's activin A antibody, brand name Pasatru, cleared the FDA on 19 August. In the pivotal 63-patient trial, new abnormal-bone lesions fell by 90% or more against placebo over 56 weeks.
Supplement makers sell K2 (menaquinone) for stronger bones and cleaner arteries. The observational signal is real; the randomised trials, so far, mostly are not.
Plain fizzy water hydrates about as well as still water and is far less corrosive to teeth than juice or soft drinks. The cautions are narrow: flavoured versions and cola, not carbonation itself.
Real deficiency shows as bone pain, muscle weakness or, in children, rickets. But US surveys suggest most people meet their needs, and both a 2011 and a 2024 review advise against routine testing in healthy adults.
Abaloparatide reliably raises bone density, so it seemed a natural candidate to help fractures knit. A randomised trial found no benefit — and healing numerically favoured placebo.
Losing a little height with age is expected. But marked loss tracks real risk: men who lost 3 cm or more had 45% higher mortality, and women who lost over 5 cm had roughly 50% higher hip-fracture risk.
Men break fewer bones than women but die more often after a hip fracture. No major body recommends screening every man, and the US task force says the evidence is simply not there yet.
The 2025 USPSTF statement keeps a B recommendation for women 65+ and for higher-risk younger postmenopausal women. The fracture benefit is real but small, and evidence gaps remain.
Adding milk, yoghurt and cheese cut hip fractures 46% in Australian aged-care residents. In the general over-50 population, dietary calcium intake shows no association with fracture risk at all.
In 388 female athletes, a per cent fat Z-score below −1.0 more than doubled sensitivity for amenorrhoea against standard BMI thresholds. It gave up specificity to do it.