In 544 pregnant women followed across Rio de Janeiro state, adverse maternal outcomes hit 18% of confirmed Oropouche infections versus 7% without, with fetal loss and haemorrhage risks roughly tripled.
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A CDC field report documents the territory's largest dengue wave in over a decade, driven almost entirely by DENV-2, with one death — the first dengue-associated death there since 2005.
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Surveillance data show 252 locally acquired dengue cases in the Tampa Bay area by 26 September, 223 of them in Hillsborough County, where an 80-year-old woman has died. Three counties have declared emergencies.
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EXPLAINERTrials show both new vaccines raise protective antibody levels in almost everyone. The unsettled question is the live-attenuated shot's safety in the older adults most likely to be hospitalised.
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WHAT THE STUDY ACTUALLY SAYSA single infusion of a pan-serotype monoclonal antibody cut viraemia and shortened fever in a 250-patient phase 2 trial in India — the first therapy to show preliminary efficacy against wild-type dengue in people.
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Across 166,390 tests during Brazil's outbreak, two TAK-003 doses were 73% effective against symptomatic dengue and 88% against hospitalisation, with no sign of waning.
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Italy logged 296 locally acquired cases in 2024, a European record. Transmission rose 19.8% per 1°C of warming, and modelling puts most of France in range for the mosquito that carries it this century.
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ANALYSISA cluster-randomised trial in Cúcuta coated water containers in 13,803 homes. Dengue incidence fell to 337 per 100,000 versus 528 in control clusters, at about US$2 per household a year.
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A rescreen of 1,000 acute febrile illness samples from Loreto found the virus circulating endemically rather than in a single outbreak, including in a remote riverine community.
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WHAT THE STUDY ACTUALLY SAYSA Brazilian laboratory study found both a prototype strain and an emergent reassortant killed neural progenitors and collapsed cortical structure. This is a dish, not a pregnancy.
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ANALYSISTwo 2026 papers describe the same shift: rural incidence now exceeds urban in some years, the peak has slid to October and November, and one in six hospitalised patients progressed to severe disease.
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Guangdong recorded 25,335 local cases in 2025 — 98% of everything China has ever reported. Genomic analysis finds every Chinese outbreak lineage matching a recent import.
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ANALYSISA CDC surveillance summary puts 2024 at 359% above the 2010–2023 annual average. The 2.8% that were locally acquired are the part that changes what mosquito control has to plan for.
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The agency stops short of calling 2025 a global surge. Its own regional tables show why: the Americas and the Indian Ocean drove the total while the Philippines and Malaysia reported fewer cases than last year.
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