For how we live.
In a double-blind trial of 65 etonogestrel-implant users with frequent or prolonged bleeding, a five-day course of tranexamic acid worked no better than placebo on any bleeding measure.
The brown facial patches come from overactive pigment cells in sun-aged skin. Triple-combination cream beats hydroquinone alone (risk ratio 1.58) and tranexamic acid helps, but relapse is the rule.
Sun-driven brown patches are hard to shift. A Cochrane review found a triple-combination cream beat hydroquinone alone; newer meta-analyses point to tranexamic acid and PRP, on thinner evidence.
Tranexamic acid cut postpartum haemorrhage in placenta praevia. Dapagliflozin nearly halved acute kidney injury after cardiac surgery. The effect sizes are very different, and so is how much to trust them.