For how we live.
Across studies, current NSAID use was tied to about a 73% higher odds of acute kidney injury, more in older people and those with existing kidney disease. The combination with two blood-pressure drugs is the real hazard.
Its guideline says antipyretics should be considered when a feverish child appears distressed, not to lower a temperature. In critically ill adults, paracetamol for fever changed nothing.
US and UK guidelines converge: a brief seizure during a fever in a young child rarely needs scans or blood tests, and paracetamol and ibuprofen do not stop them recurring.
Ten years of national anti-doping reports show NSAID declarations flat at about 45%, a significant shift away from COX-2 selective drugs, and glucocorticoids making up around 13% of all prohibited-substance findings.