For how we live.
A Finnish registry of over 123,000 women found pre-eclampsia linked to an 11% lower breast cancer risk decades later. Hormone therapy raised risk by a similar amount in both groups.
A Finnish national registry of over 11,000 women found up to 94% of endometriosis patients used menopausal hormone therapy after surgery, against 82% of a comparison group. The mix of hormones used is changing too.
Pooling decades of research, the combined estrogen-progestin regimen showed a 44% higher breast cancer risk. Estrogen-only therapy showed none in observational studies — and trials suggested it lowered risk.