For how we live.
GAIT randomised 1,583 people and found neither supplement beat placebo overall. A later network meta-analysis found effects below the clinically important threshold, and smaller still in industry-independent trials.
PACE randomised patients across 235 primary care centres and found recovery took 17 days on the drug and 16 days on placebo. For osteoarthritis the picture differs, but not flatteringly.
Ten years of national anti-doping reports show NSAID declarations flat at about 45%, a significant shift away from COX-2 selective drugs, and glucocorticoids making up around 13% of all prohibited-substance findings.