For how we live.
The largest study, comparing siblings to strip out family confounding, found no link between paracetamol in pregnancy and autism or ADHD. Guidelines still call it the preferred painkiller when one is needed.
At recommended doses it is one of the best-tolerated painkillers. The liver harm concentrates at high doses, and half of the failure cases are unintentional, often from combining products.
PACE randomised patients across 235 primary care centres and found recovery took 17 days on the drug and 16 days on placebo. For osteoarthritis the picture differs, but not flatteringly.