For how we live.
The TRACK trial was stopped early for futility. The blood thinner failed to reduce a composite of cardiovascular events, while major bleeding rose by half. Bayer, which makes the drug, was a listed collaborator.
A study of 19,539 patients echoed the randomised CONVINCE trial — but it was observational, and several of its authors work for the dialysis company that owns the data.
PISCES randomised 1,228 haemodialysis patients in Canada and Australia. The headline hazard ratio of 0.57 counts every event, not just the first — and that choice explains part of the gap.