Gout is linked to higher amputation risk in type 2 diabetes
A nationwide case-control study of 601,541 people with type 2 diabetes found gout raised the adjusted odds of lower-limb amputation by about half, with the strongest signal at the toes.
A smartphone-run gout programme hit urate targets in most patients
In a 12-month single-centre trial of 280 men, 85% on an app-supported treat-to-target model reached the serum-urate goal, against 49% on usual care. It was open-label and at one hospital.
Gout mostly hits men, and the evidence says treat the urate, not just the flares
Gout affects about one in twenty American men, driven by high uric acid. Guidelines and randomised trials back long-term urate-lowering to a target below 6 mg/dL, yet only a third of patients receive it.
Do cherries prevent gout flares? One large study says maybe — but it isn't a trial
In a study of 633 people with gout, eating cherries over two days was linked to a 35% lower risk of a flare. It is suggestive, observational evidence — no randomised trial has yet confirmed it.
Lowering high uric acid did not protect the kidneys in two randomised trials
High urate levels track with worsening kidney disease, so treating them seemed a logical way to slow it. Two trials that lowered urate with allopurinol found the kidneys declined at the same rate anyway.