JAMA published paired systematic reviews for the coming respiratory season. Both found vaccines reduced hospitalisation across age groups, with no new safety signals, though protection wanes over time.
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THE DRUG DOCKETXocova is taken after a known exposure, not after symptoms appear. In a 2,041-person trial it cut symptomatic infection by 67% through day 10.
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WHAT THE STUDY ACTUALLY SAYSA Lancet study across 547,000 adults and 925 infectious diseases finds obesity raises the risk of severe infection across almost every pathogen type. The global estimate rests on modelling, not on the cohorts themselves.
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ANALYSISAn 11,018-measurement study in 24 English intensive care units found false negative rates up to 35.3 percentage points higher in patients with darker skin tones. A neonatal study published two days later did not.
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EXPLAINERThe committee meets 18-19 September on COVID-19, hepatitis B and MMRV vaccines. RSV was dropped two days before. Adopted recommendations carry insurance and Vaccines for Children consequences.
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ANALYSISA Federal Register notice on 9 June listed eleven vaccine topics and ten scheduled votes over three days. An amended notice on 24 June listed seven topics, three votes and two days.
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