ANALYSISPooled across 216 participants, the devices beat control by 45.3% on inflammatory lesions. The trials are small, none of the devices tested is necessarily one now sold, and the market is barely regulated.
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ANALYSISUsers were slightly less likely than non-users to attempt suicide in the two to four years after treatment. The FDA's 2005 boxed warning stands, and the analysis cannot explain the direction of the finding.
4 min read
EXPLAINERTretinoin beats its own vehicle in randomised trials — though the vehicle does much of the work. In the few head-to-head trials against over-the-counter retinol, both arms improved and tretinoin irritated more.
4 min read
EXPLAINERA parental history of acne carries a pooled odds ratio of 2.91. Dairy carries 1.25, from observational studies with demonstrated publication bias — and diet appears nowhere in the treatment guideline.
5 min read
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