https://www.healthnewspapers.com/body Metabolism, weight, nutrition, and chronic disease. en-us https://www.healthnewspapers.com/body/opioid-type-gi-events-glp1-users https://www.healthnewspapers.com/body/opioid-type-gi-events-glp1-users A 411,000-patient claims study found adults on GLP-1 drugs who started oxycodone had more severe constipation and bowel obstruction at 30 days than those starting hydrocodone or tramadol. Fri, 04 Sep 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/yemen-acute-kidney-injury-cholera https://www.healthnewspapers.com/body/yemen-acute-kidney-injury-cholera Severe dehydration from diarrhoeal disease and sepsis can shut down the kidneys. In a health system with little dialysis, a review argues this is a preventable driver of death that surveillance is missing. Thu, 03 Sep 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/strength-preservation-calorie-restriction-calerie https://www.healthnewspapers.com/body/strength-preservation-calorie-restriction-calerie A transcriptomic sub-study of the CALERIE calorie-restriction trial links 151 genes to preserved leg strength during weight loss, independent of how much body mass was lost. Thu, 03 Sep 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/edmonton-vs-lancet-obesity-classification-biobank https://www.healthnewspapers.com/body/edmonton-vs-lancet-obesity-classification-biobank Applied to 411,000 UK Biobank adults, the Edmonton staging system and the Lancet Commission's clinical-obesity model classified severe disease alike but diverged on who counts as early-stage. Thu, 03 Sep 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/period-pain-dysmenorrhoea-what-works https://www.healthnewspapers.com/body/period-pain-dysmenorrhoea-what-works Cochrane reviews rate anti-inflammatory painkillers a very effective treatment for menstrual cramps, roughly doubling the odds of good pain relief. Exercise helps too, but on lower-quality evidence. Tue, 01 Sep 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/how-to-protect-your-kidneys-evidence https://www.healthnewspapers.com/body/how-to-protect-your-kidneys-evidence Kidney disease is usually silent until it is advanced, and most of it traces to diabetes and high blood pressure. Controlling those two, and getting tested, is the highest-yield protection — not kidney superfoods. Tue, 01 Sep 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/glp1-weight-loss-updated-systematic-review https://www.healthnewspapers.com/body/glp1-weight-loss-updated-systematic-review An updated Annals review now covers 38 randomised trials and 25,816 people. Tirzepatide leads the marketed drugs at 19.0% placebo-subtracted weight loss; the experimental multiagonists run higher. Tue, 01 Sep 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/gaza-oral-health-war-survey https://www.healthnewspapers.com/body/gaza-oral-health-war-survey A self-reported cross-sectional study of 599 residents found sharp deterioration across every measured dimension of oral health during the war — a neglected corner of the humanitarian-health picture. Tue, 01 Sep 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/dental-amalgam-safety-evidence https://www.healthnewspapers.com/body/dental-amalgam-safety-evidence Cochrane found composite resin restorations had almost double the failure rate in children's permanent teeth. The FDA does not recommend removing intact amalgam fillings from anyone. Tue, 01 Sep 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/staree-atorvastatin-older-adults https://www.healthnewspapers.com/body/staree-atorvastatin-older-adults STAREE randomised 9,971 Australians aged 70 and over to atorvastatin or placebo. Cardiovascular events fell by 30%. Death, dementia and persistent disability, taken together, did not move. Mon, 31 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/prasugrel-ticagrelor-switch-swedeheart https://www.healthnewspapers.com/body/prasugrel-ticagrelor-switch-swedeheart SWITCH-SWEDEHEART randomised regions rather than patients. Over 17,095 people, a default prasugrel policy did not lower ischaemic events against ticagrelor, but major bleeding was lower. Mon, 31 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/pfas-semen-parameters-meta-analysis https://www.healthnewspapers.com/body/pfas-semen-parameters-meta-analysis A meta-analysis of 14 studies and 7,465 men found little for the conventional semen parameters, and something more consistent for sperm DNA fragmentation. Mon, 31 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/metformin-geroprotector-long-trials https://www.healthnewspapers.com/body/metformin-geroprotector-long-trials Twenty-one years of cancer follow-up, multimorbidity data to 2021, and a randomised trial in frail older adults. In each, metformin did not beat placebo. Lifestyle change did. Mon, 31 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/danish-crt-targeted-left-ventricular-lead-placement https://www.healthnewspapers.com/body/danish-crt-targeted-left-ventricular-lead-placement DANISH-CRT randomised 1,000 patients to electrically targeted or conventional left ventricular lead placement. After nearly four years, death and heart failure admissions were the same. Mon, 31 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/catheter-directed-thrombolysis-pulmonary-embolism-prague-26 https://www.healthnewspapers.com/body/catheter-directed-thrombolysis-pulmonary-embolism-prague-26 PRAGUE-26 randomised 558 patients across 11 Czech hospitals. The seven-day composite fell from 6.8% to 0.7%, driven by cardiorespiratory collapse, with no clear bleeding penalty. Mon, 31 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/aspirin-omission-primary-pci-premium https://www.healthnewspapers.com/body/aspirin-omission-primary-pci-premium PREMIUM tested prasugrel alone against aspirin plus prasugrel in 2,216 STEMI patients in Japan. Monotherapy failed to show noninferiority, and the confidence interval sat above one. Mon, 31 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/acetaminophen-liver-damage-evidence https://www.healthnewspapers.com/body/acetaminophen-liver-damage-evidence At recommended doses it is one of the best-tolerated painkillers. The liver harm concentrates at high doses, and half of the failure cases are unintentional, often from combining products. Mon, 31 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/weight-loss-as-disease-modification-evidence-map https://www.healthnewspapers.com/body/weight-loss-as-disease-modification-evidence-map A Lancet review triangulates the evidence linking adiposity to multisystem disease and finds robust trial support in a short list — while an expert panel argues the drugs must be lifelong. Sun, 30 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/exercise-chronic-low-back-pain-evidence https://www.healthnewspapers.com/body/exercise-chronic-low-back-pain-evidence Cochrane found a clinically important 15.2-point pain reduction across 249 trials. A reanalysis excluding trials with fewer than 70 participants put the effect below the threshold that counts as meaningful. Sun, 30 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/beta-blocker-discontinuation-after-myocardial-infarction https://www.healthnewspapers.com/body/beta-blocker-discontinuation-after-myocardial-infarction ABYSS and SMART-DECISION together cover 6,238 stable patients. Discontinuation cleared both noninferiority margins, though the authors say the primary endpoint's composition limits what it shows. Sun, 30 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/sti-screening-intervals-home-test-accuracy https://www.healthnewspapers.com/body/sti-screening-intervals-home-test-accuracy US guidelines recommend routine chlamydia and gonorrhea screening for sexually active women under 25 and older women at higher risk. Self-collected swabs match clinician-collected ones closely. Sat, 29 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/single-af-anticoagulation-intermediate-risk https://www.healthnewspapers.com/body/single-af-anticoagulation-intermediate-risk Guidelines have hedged on anticoagulation for people with one stroke risk factor. SINGLE-AF randomised 1,803 patients in South Korea, and the events it counted were very few in both arms. Sat, 29 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/sglt2-inhibitors-kidney-heart-benefit-beyond-diabetes https://www.healthnewspapers.com/body/sglt2-inhibitors-kidney-heart-benefit-beyond-diabetes A meta-analysis of 90,000 people found these diabetes-origin drugs reduced kidney disease progression by 37% and cardiovascular events by 23%, and the benefit was similar in people who did not have diabetes. Sat, 29 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/rotavirus-vaccination-type-1-diabetes-norway https://www.healthnewspapers.com/body/rotavirus-vaccination-type-1-diabetes-norway A 740,744-child natural experiment tested a decade-old hypothesis that rotavirus vaccine might prevent type 1 diabetes. It found no protective effect — and no evidence of harm either. Sat, 29 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/occupational-noise-heart-disease-evidence https://www.healthnewspapers.com/body/occupational-noise-heart-disease-evidence WHO and ILO estimate about 17% of workers face hazardous noise. Their review of whether it causes heart disease found only low-certainty signals — one for heart-attack incidence, little for stroke or blood pressure. Sat, 29 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/aficamten-nonobstructive-hcm-acacia https://www.healthnewspapers.com/body/aficamten-nonobstructive-hcm-acacia ACACIA-HCM met both primary endpoints in symptomatic non-obstructive HCM. The gains were real but small, and one in ten patients had a reversible drop in pumping function. Sat, 29 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/urate-lowering-kidney-progression-evidence https://www.healthnewspapers.com/body/urate-lowering-kidney-progression-evidence High urate levels track with worsening kidney disease, so treating them seemed a logical way to slow it. Two trials that lowered urate with allopurinol found the kidneys declined at the same rate anyway. Fri, 28 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/migraine-triggers-reported-versus-tested https://www.healthnewspapers.com/body/migraine-triggers-reported-versus-tested A pooled analysis puts patient-reported rates at 13.9%, 8.0% and 12.0%. All of it is self-report, the heterogeneity is enormous, and the reviewers stop short of recommending avoidance. Fri, 28 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/inflammation-clinical-concept-or-marketing https://www.healthnewspapers.com/body/inflammation-clinical-concept-or-marketing A trial of an anti-inflammatory antibody cut cardiovascular events without changing lipids. A genetic study of 194,418 people found the inflammation marker everyone measures is not itself causal. Fri, 28 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/grip-strength-mortality-marker-not-lever https://www.healthnewspapers.com/body/grip-strength-mortality-marker-not-lever In half a million people, weaker grip tracked with higher mortality — a strong marker. But it reads out whole-body strength and health, not a number you move by training your hands. Fri, 28 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/glp1-diabetic-retinopathy-signal https://www.healthnewspapers.com/body/glp1-diabetic-retinopathy-signal Matched against DPP-4 inhibitors, GLP-1 users had slightly more diabetic retinopathy and more retinopathy procedures. Vision impairment and blindness did not differ — and the coding for those is poor. Fri, 28 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/physical-activity-paradox-work-evidence https://www.healthnewspapers.com/body/physical-activity-paradox-work-evidence Leisure exercise reliably protects the heart. Physical activity done for a living shows mixed or even adverse associations — and some meta-analyses find higher mortality in men with the most physically demanding jobs. Thu, 27 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/gum-disease-heart-disease-evidence https://www.healthnewspapers.com/body/gum-disease-heart-disease-evidence The American Heart Association said so in 2012. A 2026 synthesis of 19 systematic reviews found most pooled associations negligible in magnitude, and a genetic analysis found no direct causal path. Thu, 27 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/exercise-blood-pressure-isometric-question https://www.healthnewspapers.com/body/exercise-blood-pressure-isometric-question A 2023 network meta-analysis of 270 trials ranked isometric exercise first for lowering resting blood pressure. Two 2026 analyses, using ambulatory monitoring and a larger trial set, rank it among the weakest. Thu, 27 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/cannabis-chronic-pain-evidence https://www.healthnewspapers.com/body/cannabis-chronic-pain-evidence An updated systematic review of 25 randomised trials found small effects, concentrated in neuropathic pain, alongside moderate to large increases in dizziness, sedation and nausea. Long-term data barely exist. Thu, 27 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/recombinant-shingles-vaccine-cardiovascular-events https://www.healthnewspapers.com/body/recombinant-shingles-vaccine-cardiovascular-events Comparing US adults vaccinated just before and just after the changeover from the live to the recombinant shingles vaccine, researchers found a 9% lower cardiovascular burden over seven years. Wed, 26 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/anaphylaxis-evidence-base https://www.healthnewspapers.com/body/anaphylaxis-evidence-base Hospital admissions for food anaphylaxis in the UK rose 5.7% a year for two decades while the case fatality rate fell. The treatment recommendations have almost no randomised evidence behind them. Wed, 26 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/a1c-what-the-number-measures https://www.healthnewspapers.com/body/a1c-what-the-number-measures The equation converting A1c to average glucose was built from 507 people. In carriers of sickle cell trait the reading runs about 0.3 percentage points low for the same measured glucose. Wed, 26 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/salt-kidney-disease-evidence https://www.healthnewspapers.com/body/salt-kidney-disease-evidence In people who already have kidney disease, cutting salt reduced albuminuria by about 36% and lowered blood pressure. High salt also blunts standard kidney-protecting drugs — though long-term outcome trials are missing. Tue, 25 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/pelvic-floor-muscle-training-evidence https://www.healthnewspapers.com/body/pelvic-floor-muscle-training-evidence A Cochrane review found women doing pelvic floor muscle training were eight times more likely to report their stress incontinence cured than untreated women — with the strongest evidence for that one condition. Tue, 25 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/how-much-salt-sodium-evidence https://www.healthnewspapers.com/body/how-much-salt-sodium-evidence Global mean intake was 4,278 mg a day in 2021 against a recommended limit under 2,000. A week of low-sodium eating moved blood pressure in most people; a five-year trial of salt substitute cut strokes. Tue, 25 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/hepatitis-c-screening-cure-evidence https://www.healthnewspapers.com/body/hepatitis-c-screening-cure-evidence Hepatitis C is usually silent for years and is the reason for much chronic liver disease. A short course of antiviral pills cures more than 95% of cases, which is what changed the screening advice. Tue, 25 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/exercise-alone-weight-loss-dose-response https://www.healthnewspapers.com/body/exercise-alone-weight-loss-dose-response A meta-analysis of 116 randomised trials found weight, waist and body fat falling steadily up to 300 minutes a week. In one 24-week trial, 48% of participants compensated by about 308 kcal a day. Tue, 25 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/chagas-mortality-chile-national-cohort https://www.healthnewspapers.com/body/chagas-mortality-chile-national-cohort Among 17,508 notified cases from 2007 to 2021, 1.49% died of Chagas and 5.83% of other causes — with digestive complications, not cardiac ones, carrying the highest cumulative risk. Tue, 25 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/avexitide-post-bariatric-hypoglycemia-trial https://www.healthnewspapers.com/body/avexitide-post-bariatric-hypoglycemia-trial Post-bariatric hypoglycemia hits roughly 1 in 12 gastric bypass patients with sudden blood sugar crashes. Avexitide cut severe events by 55% against placebo. Tue, 25 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/isotretinoin-psychiatric-risk-meta-analysis https://www.healthnewspapers.com/body/isotretinoin-psychiatric-risk-meta-analysis Users were slightly less likely than non-users to attempt suicide in the two to four years after treatment. The FDA's 2005 boxed warning stands, and the analysis cannot explain the direction of the finding. Mon, 24 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/erectile-dysfunction-evidence-and-heart-risk https://www.healthnewspapers.com/body/erectile-dysfunction-evidence-and-heart-risk An umbrella review of the meta-analyses puts the association at RR 1.45. The AUA's guideline treats ED as a risk marker, and classes shockwave, stem cell and PRP therapy as investigational. Mon, 24 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/protein-supplementation-lipid-profiles-meta-analysis https://www.healthnewspapers.com/body/protein-supplementation-lipid-profiles-meta-analysis Pooling 32 trials, researchers found milk, whey, casein, and soy protein lowered LDL and total cholesterol slightly — but the effect shrank once weaker studies were excluded. Sun, 23 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/grpel2-mitochondrial-chaperone-mouse-obesity https://www.healthnewspapers.com/body/grpel2-mitochondrial-chaperone-mouse-obesity Mice lacking the chaperone GRPEL2 stayed leaner on a high-fat diet and kept better insulin sensitivity — an early mechanistic finding, not a treatment, and so far only in mice. Sun, 23 Aug 2026 00:00:00 GMT body https://www.healthnewspapers.com/body/rosacea-treatment-evidence https://www.healthnewspapers.com/body/rosacea-treatment-evidence Cochrane pooled 106 randomised trials in 13,631 people; a phenotype-led update reached 152 studies. The best evidence is feature-by-feature — brimonidine for redness, ivermectin and azelaic acid for pustules. Sat, 22 Aug 2026 00:00:00 GMT body